4.5 Article

Self-administered non-invasive vagus nerve stimulation therapy for severe pharmacoresistant restless legs syndrome: outcomes at 6 months

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

Noninvasive Vagus Nerve Stimulation: A New Therapeutic Approach for Pharmacoresistant Restless Legs Syndrome

Sarah Hartley et al.

Summary: The aim of this study was to investigate the effect of noninvasive vagus nerve stimulation on severe restless legs syndrome (RLS) resistant to pharmacotherapy. The results showed that after eight weeks of treatment, 66% of the participants experienced improvement in their RLS symptoms, with concomitant improvements in quality of life and mood.

NEUROMODULATION (2023)

Article Clinical Neurology

A Randomized, Placebo-Controlled Crossover Study with Dipyridamole for Restless Legs Syndrome

Diego Garcia-Borreguero et al.

Summary: The study demonstrated significant therapeutic effects of dipyridamole on both sensory and motor symptoms of restless legs syndrome, as well as on sleep. The findings confirmed the efficacy predicted from preclinical studies and highlighted the key role of adenosine in restless legs syndrome.

MOVEMENT DISORDERS (2021)

Review Neurosciences

A Review of Parameter Settings for Invasive and Non-invasive Vagus Nerve Stimulation (VNS) Applied in Neurological and Psychiatric Disorders

Sean L. Thompson et al.

Summary: Vagus nerve stimulation (VNS) is a well-established form of neuromodulation with potential applications in various disorders, but there is currently a lack of consensus on the optimal stimulation parameters. This therapy has shown promise in treating conditions such as epilepsy, depression, and post-stroke rehabilitation. The article provides a historical perspective on the evolution and applications of VNS in different fields.

FRONTIERS IN NEUROSCIENCE (2021)

Review Medicine, Research & Experimental

Gut-brain communication and obesity: understanding functions of the vagus nerve

Hans-Rudolf Berthoud et al.

Summary: With advancements in modern neurobiology technology, the understanding of the role of vagal afferents in gut-brain communication has started to change. Current clinical approaches to utilizing gut-brain communication for treating obesity and metabolic disease are limited to a few gut hormones. However, a more comprehensive understanding of specific neuronal populations may lead to the development of more selective and effective neuromodulation approaches.

JOURNAL OF CLINICAL INVESTIGATION (2021)

Article Neurosciences

Cognition-Enhancing Vagus Nerve Stimulation Alters the Epigenetic Landscape

Teresa H. Sanders et al.

JOURNAL OF NEUROSCIENCE (2019)

Review Respiratory System

Treating restless Legs syndrome in the context of sleep disordered breathing comorbidity

Sofia Romero-Peralta et al.

EUROPEAN RESPIRATORY REVIEW (2019)

Review Clinical Neurology

Management of treatment failure in restless legs syndrome (Willis-Ekbom disease)

Diego Garcia-Borreguero et al.

SLEEP MEDICINE REVIEWS (2018)

Article Neurosciences

Pivotal Role of Adenosine Neurotransmission in Restless Legs Syndrome

Sergi Ferre et al.

FRONTIERS IN NEUROSCIENCE (2018)

Review Clinical Neurology

Comorbidities, treatment, and pathophysiology in restless legs syndrome

Claudia Trenkwalder et al.

LANCET NEUROLOGY (2018)

Article Multidisciplinary Sciences

MEIS1 variant as a determinant of autonomic imbalance in Restless Legs Syndrome

Jerome Thireau et al.

SCIENTIFIC REPORTS (2017)

Article Clinical Neurology

Vagus nerve stimulation

Dzenan Lulic et al.

NEUROSURGICAL FOCUS (2009)

Article Clinical Neurology

Augmentation as a treatment complication of restless legs syndrome: Concept and management

Diego Garcia-Borreguero et al.

MOVEMENT DISORDERS (2007)

Article Neurosciences

Vagus nerve stimulation (VNS) for major depressive episodes: One year outcomes

LB Marangell et al.

BIOLOGICAL PSYCHIATRY (2002)