4.4 Review

Opportunities and challenges for the application of microfluidic technologies in point-of-care veterinary diagnostics

Journal

MOLECULAR AND CELLULAR PROBES
Volume 30, Issue 5, Pages 331-341

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.mcp.2016.07.004

Keywords

Point-of-care; Veterinary diagnostics; Microfluidics; Lateral flow immunoassays; Paper-based microfluidics; Dipstick test

Funding

  1. Moredun Scientific Ltd.
  2. Heriot-Watt University

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There is a growing need for low-cost, rapid and reliable diagnostic results in veterinary medicine. Point-of-care (POC) tests have tremendous advantages over existing laboratory-based tests, due to their intrinsic low-cost and rapidity. A considerable number of POC tests are presently available, mostly in dipstick or lateral flow formats, allowing cost-effective and decentralised diagnosis of a wide range of infectious diseases and public health related threats. Although, extremely useful, these tests come with some limitations. Recent advances in the field of microfluidics have brought about new and exciting opportunities for human health diagnostics, and there is now great potential for these new technologies to be applied in the field of veterinary diagnostics. This review appraises currently available POC tests in veterinary medicine, taking into consideration their usefulness and limitations, whilst exploring possible applications for new and emerging technologies, in order to widen and improve the range of POC tests available. (C) 2016 Elsevier Ltd. All rights reserved.

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