Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 236, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jpba.2023.115649
Keywords
Solid-state properties; Analytical techniques; Sample preparation; Product performance; Dosage form; Process analytics
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The solid state of matter is the preferred starting point for designing pharmaceutical products, and the importance of solid-state analytical methods is emphasized. This paper critically analyzes the challenges related to solid-state analytics and provides considerations and suggestions for feasible and meaningful pharmaceutical analysis.
The solid state of matter is the preferred starting point for designing a pharmaceutical product. This is driven by both patient preferences and the relative ease of supplying a solid pharmaceutical product with desired quality and performance. Solid form diversity is increasingly prevalent as a crucial element in designing these products, which underpins the importance of solid-state analytical methods. This paper provides a critical analysis of challenges related to solid-state analytics, as well as considerations and suggestions for feasible and meaningful pharmaceutical analysis.
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