4.6 Article

Rapid and sensitive dilute-and-shoot analysis using LC-MS-MS for identification of multi-class psychoactive substances in human urine

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Development of a Simple, Underivatized Method for Rapid Determination of Free Amino Acids in Honey Using Dilute-and-Shoot Strategy and Liquid Chromatography-Tandem Mass Spectrometry

Wen Ma et al.

Summary: This study developed a simple, fast and reliable method for the determination of 20 free amino acids in honey samples. The method achieved accurate results through a dilute-and-shoot strategy and hydrophilic interaction liquid chromatography tandem mass spectrometry. The method demonstrated advantages such as short detection time, wide linear range, high sensitivity, and negligible matrix effect.

MOLECULES (2022)

Article Chemistry, Analytical

Engineering an integrated system with a high pressure polymeric microfluidic chip coupled to liquid chromatography-mass spectrometry (LC-MS) for the analysis of abused drugs

Pin-Chuan Chen et al.

Summary: A novel high-pressure resistant microfluidic chip was successfully fabricated and coupled with an LC-MS system for efficient and precise bioanalysis. The experimental results demonstrated significant reproducibility, stability and durability of the chip, making it an effective tool for biological sample analysis.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

Article Chemistry, Analytical

A novel HPLC-DAD method with dilute-and-shoot sample preparation technique for the determination of buprofezin, dinobuton and chlorothalonil in food, environmental and biological samples

Weldejeworgis Hndeya Gebrehiwot et al.

Summary: The study developed a method for simultaneous determination of three pesticides and investigated the degradation and behavior of these pesticides under different conditions. The method showed good linearity and precision, high sensitivity, simplicity, robustness, speed, and provided satisfactory recovery rates.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY (2021)

Article Medicine, Legal

Simultaneous LC-MS/MS screening for multiple phenethylamine-type conventional drugs and new psychoactive substances in urine

Shu-Yu Fan et al.

Summary: The abuse of new psychoactive substances poses risks to public health and safety, with phenethylamines being the main reported substances. A study introduced an LC-MS/MS method for detecting 74 conventional and artificial phenethylamines in urine samples, which was validated through the analysis of authentic urine samples, showing 20 samples tested positive for seven phenethylamines.

FORENSIC SCIENCE INTERNATIONAL (2021)

Review Chemistry, Analytical

Redefining dilute and shoot: The evolution of the technique and its application in the analysis of foods and biological matrices by liquid chromatography mass spectrometry

Brett Greer et al.

Summary: With laboratories seeking to expand analytical capabilities, there has been a shift towards generic sample clean-up techniques like dilute-and-shoot. This methodology is simple, versatile, and facilitates high sample throughput and analysis of various analyte classes.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Analysis of amphetaminic drug compounds in urine by headspace-dielectric barrier discharge ionization-mass spectrometry

Ahsan Habib et al.

ARABIAN JOURNAL OF CHEMISTRY (2020)

Editorial Material Medicine, General & Internal

The global drug problem: change but not progression

Pamela Das et al.

LANCET (2019)

Article Biochemical Research Methods

Comparison of Liquid/Liquid and Solid-Phase Extraction for Alkaline Drugs

Matthew P. Juhascik et al.

JOURNAL OF CHROMATOGRAPHIC SCIENCE (2009)

Review Biochemical Research Methods

Bioanalysis of drugs by liquid-phase microextraction coupled to separation techniques

S Pedersen-Bjergaard et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2005)

Article Medicine, Legal

One-step liquid-liquid extraction of cocaine from urine samples for gas chromatographic analysis

M Farina et al.

FORENSIC SCIENCE INTERNATIONAL (2002)