4.7 Article

Synthesis of Isoquinolines and Related Heterocycles under Visible-Light Conditions

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 88, Issue 22, Pages 15750-15760

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.3c01782

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Visible-light catalysis is an effective method for constructing various types of compounds. Further advancements are needed, but a seamless reaction pathway has been presented for synthesizing compounds with 6-membered ring nitrogen-containing heterocycles.
Visible-light catalysis is now widely acknowledged as a potent approach for efficiently constructing various types of frameworks, particularly bioactive compounds, with high yields. However, there is still a strong need for further advancements in these methods because certain delicate compounds cannot be synthesized due to structural sensitivity. In this context, a seamless reaction pathway toward 6-membered ring nitrogen-containing heterocycles is presented here, offering access to isoquinoline derivatives and related heterocycles.

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