Pretreatment brain CT perfusion thresholds for predicting final infarct volume in distal medium vessel occlusions

Article Clinical Neurology

Predictors of Good Clinical Outcome after Thrombectomy for Distal Medium Vessel Occlusions

Franny Hulscher et al.

Summary: Older age, longer puncture to recanalization time, and higher baseline core volume are associated with poorer clinical outcomes after mechanical thrombectomy for DMVO, while successful recanalization is associated with better outcomes.

WORLD NEUROSURGERY (2022)

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Article Clinical Neurology

Accuracy of CT Perfusion-Based Core Estimation of Follow-up Infarction Effects of Time Since Last Known Well

Amrou Sarraj et al.

Summary: This study assessed the accuracy of baseline CT perfusion (CTP) ischemic core estimates and found that overestimation of infarct volume may occur in patients imaged within 90 minutes and achieving reperfusion within 120 minutes. The use of a more conservative threshold can eliminate significant overestimation cases.

NEUROLOGY (2022)

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Article Clinical Neurology

Thrombectomy for distal medium vessel occlusion with a new generation of Stentretriever (Tigertriever 13)

Adrien Guenego et al.

Summary: The study evaluated the safety and efficacy of the Tigertriever13 stent retriever in acute ischemic stroke patients with distal, medium vessel occlusions. Results showed that mechanical thrombectomy using Tigertriever13 was safe and effective for DMVO, with favorable clinical and anatomical outcomes similar to those with proximal occlusions.

INTERVENTIONAL NEURORADIOLOGY (2022)

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Article Clinical Neurology

Early Neurological Improvement Predicts Clinical Outcome After Thrombectomy for Distal Medium Vessel Occlusions

Maud Wang et al.

Summary: This study aimed to investigate the impact of early neurological improvement (ENI) after mechanical thrombectomy (MT) for distal medium vessel occlusions (DMVO) in acute ischemic stroke (AIS). The results showed that ENI was a strong independent predictor of good clinical outcome, and the use of intravenous tissue plasminogen activator (IVtPA) was a positive predictor of ENI.

FRONTIERS IN NEUROLOGY (2022)

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Article Clinical Neurology

Time-to-Maximum of the Tissue Residue Function Improves Diagnostic Performance for Detecting Distal Vessel Occlusions on CT Angiography

S. A. Amukotuwa et al.

Summary: The study demonstrates that using CTP-derived time-to-maximum of the tissue residue function maps significantly improves the diagnostic performance for detecting distal arterial occlusions in acute stroke imaging, enhancing readers' diagnostic confidence and speed.

AMERICAN JOURNAL OF NEURORADIOLOGY (2021)

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Article Clinical Neurology

Treatment and Outcome in Stroke Patients With Acute M2 Occlusion and Minor Neurological Deficits

Tomas Dobrocky et al.

Summary: This study compared the outcomes of intravenous thrombolysis (IVT) with endovascular therapy (EVT) (+/- IVT) and IVT with mechanical thrombectomy (MT) in patients with peripheral middle cerebral artery occlusions and minor neurological deficits. The results showed similar effectiveness between IVT and EVT, as well as IVT and MT, in these patients, with a potential benefit of EVT in those treated after 2015.

STROKE (2021)

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Article Clinical Neurology

Ischemic Core Overestimation on Computed Tomography Perfusion

Alvaro Garcia-Tornel et al.

Summary: This study found that poor collateral status and earlier onset to imaging time can lead to overestimation of ischemic core on CT perfusion (CTP) in patients with large-vessel stroke. These factors are important considerations when estimating the extent of brain tissue damage in patients undergoing endovascular therapy with reperfusion achieved.

STROKE (2021)

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Article Clinical Neurology

Distal Medium Vessel Occlusions Can Be Accurately and Rapidly Detected Using Tmax Maps

Shalini A. Amukotuwa et al.

Summary: The study found that Tmax maps derived from CT perfusion can accurately and rapidly identify patients with DMVOs, demonstrating high sensitivity and specificity for this condition.

STROKE (2021)

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Article Clinical Neurology