Effect of group electronegativity on spectroscopic, biological, chromogenic sensing and optical properties of 2-formyl-benzene sulfonic acid sodium salt-based Schiff bases

In this study, 2-formylbenzenesulfonic acid sodium salt-based Schiff bases were synthesized from the reactions of 2-formylbenzenesulfonic acid sodium salt with 2-amino-4-chlorophenol and 2-amino-4-methylphenol. The structure of the compounds was determined by FTIR, UV-Vis and NMR spectroscopy methods using both experimental and DFT methods. The anion sensor properties of the compounds were investigated both UV-Vis spectroscopically and calorimetrically. In addition, the antimicrobial activities, interactions with DNA, DNA cleavage and antioxidant activities of Schiff bases were investigated. Additionally, the effects of group electronegativity on the spectroscopic, biological, chromogenic sensing and optical properties of chlorine and methyl side groups and sodium 2-sulfobenzalidene-aminophenol-based Schiff bases were investigated.

Automated summary

In this study, 2-formylbenzenesulfonic acid sodium salt-based Schiff bases were synthesized and their structures were determined by various spectroscopy methods. The compounds were found to have anion sensing properties and were also investigated for their antimicrobial activities, interactions with DNA, DNA cleavage, and antioxidant activities. Furthermore, the effects of group electronegativity on the spectroscopic, biological, chromogenic sensing, and optical properties of the compounds were studied.