Related references
Note: Only part of the references are listed.Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator
Brian E. Krumm et al.
BIOCHEMISTRY (2023)
Molecular mechanism of biased signaling at the kappa opioid receptor
Amal El Daibani et al.
NATURE COMMUNICATIONS (2023)
Structures of the entire human opioid receptor family
Yue Wang et al.
CELL (2023)
The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites
Janik B. Hedderich et al.
NATURE COMMUNICATIONS (2022)
A lowly populated, transient β-sheet structure in monomeric Aβ1-42 identified by multinuclear NMR of chemical denaturation
Tayeb Kakeshpour et al.
BIOPHYSICAL CHEMISTRY (2021)
Design, Structural Optimization, and Characterization of the First Selective Macrocyclic Neurotensin Receptor Type 2 Non-opioid Analgesic
Magali Chartier et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors
Lauren M. Slosky et al.
CELL (2020)
Methods and Approaches for the Solid-Phase Synthesis of Peptide Alcohols
Fernando J. Ferrer-Gago et al.
CHEMPLUSCHEM (2020)
Binding kinetics of ligands acting at GPCRs
David A. Sykes et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2019)
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Scott A. Hollingsworth et al.
NATURE COMMUNICATIONS (2019)
Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain
Guillaume Ferre et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia
Emilie Eiselt et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Optimization and 13CH3 methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies
Fabian Bumbak et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)
The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors
Lisa Joedicke et al.
NATURE CHEMICAL BIOLOGY (2018)
Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8-13)
Marc Sousbie et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
A proline switch explains kinetic heterogeneity in a coupled folding and binding reaction
Franziska Zosel et al.
NATURE COMMUNICATIONS (2018)
Drug-Target Kinetics in Drug Discovery
Peter J. Tonge
ACS CHEMICAL NEUROSCIENCE (2018)
The signaling signature of the neurotensin type 1 receptor with endogenous ligands
Elie Besserer-Offroy et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues
Roberto Fanelli et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Bitopic Ligands and Metastable Binding Sites: Opportunities for G Protein-Coupled Receptor (GPCR) Medicinal Chemistry
Philipp Fronik et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Structure and Function of Peptide-Binding G Protein-Coupled Receptors
Fan Wu et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse
Larry S. Barak et al.
ACS CHEMICAL BIOLOGY (2016)
Coupled binding and folding of intrinsically disordered proteins: what can we learn from kinetics?
Stefano Gianni et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2016)
The role of kinetic context in apparent biased agonism at GPCRs
Carmen Klein Herenbrink et al.
NATURE COMMUNICATIONS (2016)
A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor
Manuel Grundmann et al.
CELL CHEMICAL BIOLOGY (2016)
Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y2 Receptor Binding and Activation
Anette Kaiser et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)
NMR structure and dynamics of the agonist dynorphin peptide bound to the human kappa opioid receptor
Casey O'Connor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structural prerequisites for G-protein activation by the neurotensin receptor
Brian E. Krumm et al.
NATURE COMMUNICATIONS (2015)
Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies
Daniel J. Scott et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2014)
SnapShot: GPCR-Ligand Interactions
Eshan Ghosh et al.
CELL (2014)
The binding mechanisms of intrinsically disordered proteins
Jakob Dogan et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2014)
Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin
Esben M. Quistgaard et al.
PROTEIN SCIENCE (2014)
Structure-Function of the G Protein-Coupled Receptor Superfamily
Vsevolod Katritch et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)
Cooperative Unfolding of Compact Conformations of the Intrinsically Disordered Protein Osteopontin
Dennis Kurzbach et al.
BIOCHEMISTRY (2013)
Intermolecular interactions between the neurotensin and the third extracellular loop of human neurotensin 1 receptor
Gregory Da Costa et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2013)
Activation and allosteric modulation of a muscarinic acetylcholine receptor
Andrew C. Kruse et al.
NATURE (2013)
Diverse Roles of Neurotensin Agonists in the Central Nervous System
Mona Boules et al.
Frontiers in Endocrinology (2013)
Modulation of the neurotensin solution structure in the presence of ganglioside GM1 bicelle
Ummul Liha Khatun et al.
BIOPHYSICAL CHEMISTRY (2012)
Structure of the agonist-bound neurotensin receptor
Jim F. White et al.
NATURE (2012)
GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor
Miriam C. Peeters et al.
FASEB JOURNAL (2011)
Kinetic Recognition of the Retinoblastoma Tumor Suppressor by a Specific Protein Target
Lucia B. Chemes et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction
Annett Bachmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
19F NMR Studies of α-Synuclein Conformation and Fibrillation
Conggang Li et al.
BIOCHEMISTRY (2009)
The courtship of proteins: Understanding the encounter complex
Marcellus Ubbink
FEBS LETTERS (2009)
Kinetic Advantage of Intrinsically Disordered Proteins in Coupled Folding-Binding Process: A Critical Assessment of the Fly-Casting Mechanism
Yongqi Huang et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P. Jeffrey Conn et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Interaction of urea with amino acids:: Implications for urea-induced protein denaturation
Martin C. Stumpe et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Critical role for the second extracellular loop in the binding of both orthosteric and allosteric g protein-coupled receptor Ligands
Vimesh A. Avlani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Allosteric GPCR modulators: taking advantage of permissive receptor pharmacology
Katie Leach et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
NMR solution structure of neurotensin in membrane-mimetic environments: Molecular basis for neurotensin receptor recognition
Jerome Coutant et al.
BIOCHEMISTRY (2007)
An on-pathway intermediate in the folding of a PDZ domain
Ylva Ivarsson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Probing conformational disorder in neurotensin by two-dimensional solid-state NMR and comparison to molecular dynamics simulations
H Heise et al.
BIOPHYSICAL JOURNAL (2005)
Protein production by auto-induction in high-density shaking cultures
FW Studier
PROTEIN EXPRESSION AND PURIFICATION (2005)
Evaluation of lactam-bridged neurotensin analogues adjusting ψ(Pro10) close to the experimentally derived bioactive conformation of NT(8-13)
H Bittermann et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Conformation of a peptide ligand bound to its G-protein coupled receptor
H Inooka et al.
NATURE STRUCTURAL BIOLOGY (2001)
Share Paper
