Related references
Note: Only part of the references are listed.Psychedelics as Transformative Therapeutics
Bryan L. Roth et al.
AMERICAN JOURNAL OF PSYCHIATRY (2023)
Establishment of multi-stage intravenous self-administration paradigms in mice
Lauren M. M. Slosky et al.
SCIENTIFIC REPORTS (2022)
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
Nicholas M. Barnes et al.
PHARMACOLOGICAL REVIEWS (2021)
Spotlight on Pimavanserin Tartrate and Its Therapeutic Potential in the Treatment of Major Depressive Disorder: The Evidence to Date
Vicki Soogrim et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2021)
Psychedelics and Other Psychoplastogens for Treating Mental Illness
Maxemiliano V. Vargas et al.
FRONTIERS IN PSYCHIATRY (2021)
Role of serotonin in body weight, insulin secretion and glycaemic control
Teodora Georgescu et al.
JOURNAL OF NEUROENDOCRINOLOGY (2021)
OPLS4: Improving Force Field Accuracy on Challenging Regimes of Chemical Space
Chao Lu et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2021)
hERG toxicity assessment: Useful guidelines for drug design
Amanda Garrido et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor-Positive Allosteric Modulators with Enhanced Drug-like Properties
Eric A. Wold et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor
Kuglae Kim et al.
CELL (2020)
Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor
Christopher T. Wild et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
In vitro functional evaluation of isolaureline, dicentrine and glaucine enantiomers at 5-HT2 and α1 receptors
Hui Li Heng et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2019)
Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts
Eric A. Wold et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Positive-allosteric modulation of the 5-HT2C receptor: implications for neuropsychopharmacology and neurotherapeutics
Jia Zhou et al.
NEUROPSYCHOPHARMACOLOGY (2019)
Identification of dual role of piperazine-linked phenyl cyclopropyl methanone as positive allosteric modulator of 5-HT2C and negative allosteric modulator of 5-HT2B receptors
Kartikey Singh et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development
Eric A. Wold et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2019)
CB1R mediates oleamide's reward while 5HT2cR mediates aversion in the nucleus accumbens shell of rats
Monica Mendez-Diaz et al.
NEUROSCIENCE LETTERS (2019)
In Vivo and In Vitro Analyses of Novel Peptidomimetic Disruptors for the Serotonin 5-HT2C Receptor Interaction With Phosphatase and Tensin Homolog
Claudia A. Soto et al.
FRONTIERS IN PHARMACOLOGY (2019)
Endogenous Serotonin 5-HT2A and 5-HT2C Receptors Associate in the Medial Prefrontal Cortex
Amanda E. Price et al.
ACS CHEMICAL NEUROSCIENCE (2019)
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology
Yao Peng et al.
CELL (2018)
ProTox-II: a webserver for the prediction of toxicity of chemicals
Priyanka Banerjee et al.
NUCLEIC ACIDS RESEARCH (2018)
Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction
Daniel E. Felsing et al.
PLOS ONE (2018)
GPCR Allosteric Modulators: Mechanistic Advantages and Therapeutic Applications
Eric A. Wold et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2018)
Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers
Imane Moutkine et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
A Positive Allosteric Modulator of the Serotonin 5-HT2c Receptor for Obesity
Javier Garcia-Carceles et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery
Travis T. Wager et al.
ACS CHEMICAL NEUROSCIENCE (2016)
Endocannabinoids and sleep
Oscar Prospero-Garcia et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2016)
5-HT2C receptors in psychiatric disorders: A review
A. Chagraoui et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2016)
Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2cR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity
Noelle C. Anastasio et al.
ACS CHEMICAL NEUROSCIENCE (2015)
The role of serotonin 5-HT2A receptors in memory and cognition
Gongliang Zhang et al.
FRONTIERS IN PHARMACOLOGY (2015)
Serotonin 5-HT2 Receptor Interactions with Dopamine Function: Implications for Therapeutics in Cocaine Use Disorder
Leonard L. Howell et al.
PHARMACOLOGICAL REVIEWS (2015)
Harnessing Allostery: A Novel Approach to Drug Discovery
Shaoyong Lu et al.
MEDICINAL RESEARCH REVIEWS (2014)
Exploration of Synthetic Approaches and Pharmacological Evaluation of PNU-69176E and Its Stereoisomer as 5-HT2C Receptor Allosteric Modulators
Chunyong Ding et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Automated design of ligands to polypharmacological profiles
Jeremy Besnard et al.
NATURE (2012)
Selective serotonin 5-HT2C receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues
Kathryn A. Cunningham et al.
NEUROPHARMACOLOGY (2011)
Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties
Travis T. Wager et al.
ACS CHEMICAL NEUROSCIENCE (2010)
Oleamide administered into the nucleus accumbens shell regulates feeding behaviour via CB1 and 5-HT2C receptors
Edgar Soria-Gomez et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
Interaction of 5-HT2A and 5-HT2C Receptors in R(-)-2,5-Dimethoxy-4-iodoamphetamine-Elicited Head Twitch Behavior in Mice
W. E. Fantegrossi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
The Serotonin 5-HT2C Receptor in Medial Prefrontal Cortex Exerts Rheostatic Control over the Motivational Salience of Cocaine-Associated Cues: New Observations from Preclinical Animal Research
Kathryn A. Cunningham et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P. Jeffrey Conn et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
5-HT2A and 5-HT2C Receptors Exert Opposing Effects on Locomotor Activity in Mice
Adam L. Halberstadt et al.
NEUROPSYCHOPHARMACOLOGY (2009)
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions
Mark J. Millan et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Locomotor response to novelty as a predictor of reactivity to aversive stimuli in the rat
David A. White et al.
BRAIN RESEARCH (2007)
Estrous cycle influence on individual differences in the response to novelty and cocaine in female rats
SL Sell et al.
BEHAVIOURAL BRAIN RESEARCH (2005)
Locomotor activity predicts acquisition of self-administration behavior but not cocaine intake
JM Mitchell et al.
BEHAVIORAL NEUROSCIENCE (2005)
Contribution of serotonin (5-hydroxytryptamine;: 5-HT) 5-HT2 receptor subtypes to the hyperlocomotor effects of cocaine:: Acute and chronic pharmacological analyses
M Filip et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Serotonin 5-HT2A receptors underlie increased motor behaviors induced in dopamine-depleted rats by intrastriatal 5-HT2A/2C agonism
C Bishop et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Positive allosteric modulator of the human 5-HT2C receptor
W Bin Im et al.
MOLECULAR PHARMACOLOGY (2003)
No hypothermic response to serotonin in 5-HT7 receptor knockout mice
PB Hedlund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism
GA Higgins et al.
PSYCHOPHARMACOLOGY (2003)
Modulation of 5-HT2A receptor-mediated head-twitch behaviour in the rat by 5-HT2C receptor agonists
SP Vickers et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2001)
Influence of the 5-HT2C receptor antagonist SB242,084 on behaviour produced by the 5-HT2 agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramine
GA Higgins et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)