4.7 Article

Associations between exposure to ambient particulate matter and advanced liver fibrosis in Chinese MAFLD patients

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Long-term exposure to air pollution and incident non-alcoholic fatty liver disease and cirrhosis: A cohort study

Fu-Rong Li et al.

Summary: This study found that long-term exposure to air pollution is associated with an increased risk of NAFLD and cirrhosis among the UK population.

LIVER INTERNATIONAL (2023)

Article Environmental Sciences

Long-term exposure to air pollution, habitual physical activity and risk of non-alcoholic fatty liver disease: A prospective cohort study

Shengzhi Sun et al.

Summary: Long-term exposure to PM2.5 is positively associated with NAFLD, while engaging in physical activity is inversely associated with NAFLD. The benefits of physical activity on NAFLD remain consistent across various levels of PM2.5 exposure.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2022)

Article Gastroenterology & Hepatology

Exposure to air pollution is associated with an increased risk of metabolic dysfunction-associated fatty liver disease

Bing Guo et al.

Summary: This study found that long-term exposure to ambient air pollution may increase the odds of MAFLD in Chinese adults, especially in males, smokers, alcohol drinkers, high-fat diet consumers, and individuals with central obesity. These effects may be exacerbated by unhealthy lifestyle habits.

JOURNAL OF HEPATOLOGY (2022)

Review Gastroenterology & Hepatology

Metabolic (dysfunction)-associated fatty liver disease in individuals of normal weight

Mohammed Eslam et al.

Summary: Metabolic (dysfunction)-associated fatty liver disease (MAFLD) is a chronic liver disease associated with obesity, but can also affect individuals of normal weight. It increases the risk of liver disease, cancer, and other cardiometabolic conditions. The clinical profile and pathophysiology of MAFLD in normal weight individuals are not well understood.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2022)

Article Environmental Sciences

PM2.5 air pollution exposure and nonalcoholic fatty liver disease in the Nationwide Inpatient Sample

Trang VoPham et al.

Summary: This study found a positive association between ambient PM2.5 exposure and odds of NAFLD among hospitalized patients using nationwide cross-sectional analysis. The effect of this association varied based on factors such as age, race, diabetes, smoking, and region.

ENVIRONMENTAL RESEARCH (2022)

Article Biochemistry & Molecular Biology

Combined exposure to PM2.5 and high-fat diet facilitates the hepatic lipid metabolism disorders via ROS/miR-155/PPAR? pathway

Zhou Du et al.

Summary: This study aimed to investigate the combined negative effects of PM2.5 and high-fat diet (HFD) on liver lipid metabolism. The results showed that PM2.5 exposure resulted in increased liver fat content in HFD-fed mice and there was a synergistic effect between PM2.5 and HFD on hepatic lipotoxicity.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

Article Environmental Sciences

Long-Term Exposure to Fine Particulate Matter and the Risk of Chronic Liver Diseases: A Meta-Analysis of Observational Studies

Jing Sui et al.

Summary: This meta-analysis study reviewed epidemiological studies to strengthen the evidence for the association between PM2.5 and chronic liver disease. The results showed that long-term exposure to PM2.5 was associated with an increased risk of chronic liver disease, particularly liver cancer, liver cirrhosis, and fatty liver disease.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Article Environmental Sciences

Urbanization, ambient air pollution, and prevalence of chronic kidney disease: A nationwide cross-sectional study

Ze Liang et al.

Summary: The study found an association between PM2.5, NO2, and increased odds of CKD prevalence, especially in areas with medium urbanization levels. This suggests the importance of strengthening environmental management in these regions.

ENVIRONMENT INTERNATIONAL (2021)

Review Medicine, Research & Experimental

The influence of PM2.5 exposure on non-alcoholic fatty liver disease

Jiaxin Chen et al.

Summary: Exposure to PM2.5 is significantly related to the incidence of NAFLD, impacting the classic multiple hits hypothesis and promoting disease development through pathways such as disrupting intestinal epithelium, triggering endoplasmic reticulum stress, and inducing abnormal expression of specific microRNA or inflammatory factors.

LIFE SCIENCES (2021)

Article Biochemistry & Molecular Biology

PM2.5-exposed hepatocytes induce hepatic stellate cells activation by releasing TGF-β1

Lin Leilei et al.

Summary: Recent studies have shown that TGF-beta 1 secreted from hepatocytes exposed to PM2.5 may lead to activation of hepatic stellate cells, potentially contributing to liver fibrosis.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)

Article Gastroenterology & Hepatology

Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease

Ditlev Nytoft Rasmussen et al.

Summary: Alcohol is the most common cause of liver-related mortality and morbidity. This study aimed to evaluate and compare the prognostic performance of elastography and blood-based markers in predicting liver-related events, severe infection, and all-cause mortality in patients with a history of excess drinking. The results showed that transient elastography, enhanced liver fibrosis test, and 2D shear-wave elastography are highly accurate prognostic markers in patients with alcohol-related liver disease.

JOURNAL OF HEPATOLOGY (2021)

Review Gastroenterology & Hepatology

Molecular and cellular mechanisms of liver fibrosis and its regression

Tatiana Kisseleva et al.

Summary: Chronic liver injury results in liver inflammation and fibrosis, which can be reversed by eliminating activated myofibroblasts and resorbing the fibrous scar. Understanding the molecular mechanisms underlying liver fibrosis and its reversibility can lead to the identification of new therapeutic targets for liver fibrosis treatment.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

Article Gastroenterology & Hepatology

Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation

Fei Chen et al.

HEPATOLOGY (2020)

Review Environmental Sciences

Inflammatory effects of particulate matter air pollution

Ruben D. Arias-Perez et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2020)

Review Biochemistry & Molecular Biology

Liver fibrosis: Pathophysiology, pathogenetic targets and clinical issues

Maurizio Parola et al.

MOLECULAR ASPECTS OF MEDICINE (2019)

Review Environmental Sciences

Ambient air pollution and lipid profile: Systematic review and meta-analysis

Vania Gaio et al.

ENVIRONMENTAL POLLUTION (2019)

Article Engineering, Environmental

Satellite-Derived 1-km-Resolution PM1 Concentrations from 2014 to 2018 across China

Jing Wei et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2019)

Article Environmental Sciences

Long-term high air pollution exposure induced metabolic adaptations in traffic policemen

Chaochao Tan et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2018)

Article Gastroenterology & Hepatology

Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis

Stuart McPherson et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2017)

Article Gastroenterology & Hepatology

Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models

Ze Zheng et al.

JOURNAL OF HEPATOLOGY (2015)

Review Endocrinology & Metabolism

Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome

Hannele Yki-Jarvinen

LANCET DIABETES & ENDOCRINOLOGY (2014)

Review Biotechnology & Applied Microbiology

Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies

Abderrahim Nemmar et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Article Public, Environmental & Occupational Health

Modeling the Association Between Particle Constituents of Air Pollution and Health Outcomes

Elizabeth Mostofsky et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2012)

Article Public, Environmental & Occupational Health

Employment and Physical Activity in the U.S.

Dane R. Van Domelen et al.

AMERICAN JOURNAL OF PREVENTIVE MEDICINE (2011)

Article Gastroenterology & Hepatology

Diagnosis of Fibrosis and Cirrhosis Using Liver Stiffness Measurement in Nonalcoholic Fatty Liver Disease

Vincent Wai-Sun Wong et al.

HEPATOLOGY (2010)

Article Gastroenterology & Hepatology

A position statement on NAFLD/NASH based on the EASL 2009 special conference

Vlad Ratziu et al.

JOURNAL OF HEPATOLOGY (2010)