Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 16, Issue 10, Pages 825-845Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557516666160211120835
Keywords
Anti-bacterial; anticonvulsant; antifungal; anti-inflammatory; analgesic; anticancer; oxadiazole
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Recently, there has been wide interest in compounds containing the oxadiazole scaffold because of their unique chemical structure and their broad spectrum of biological properties. This review provides readers with an overview of the main synthetic methodologies for oxadiazoles and of their broad spectrum of pharmacological activities such as, anti-microbial, anti-fungal activity, antiviral, anti-tubercular, anti-inflammatory, anti-convulsant, anti-angiogenic, anti-proliferative, analgesic, anti-oedema and in alzheimer activity, which were reported over the past years.
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