4.7 Article

Rhodium(III)-catalyzed C7-position C-H alkenylation and alkynylation of indolines

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 13, Pages 2532-2535

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc09330e

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Funding

  1. Nanyang Technological University, Singapore Ministry of Education Academic Research Fund [ETRP 1002 111, MOE2010-T2-2-067, MOE 2011-T2-1-013]

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A Rh(III)-catalyzed regioselective C-H alkenylation and alkynylation of indolines is described. This protocol relies on the use of a removable pyridinyl directing group to access valuable C-7 functionalized indoline scaffolds with ample substrate scope and broad functional group tolerance.

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