4.7 Article

Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 2, Pages 406-408

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc08178a

Keywords

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Funding

  1. National Natural Science Foundation of China [51373117, 51303126]
  2. Key Project of Tianjin Natural Science Foundation [13JCZDJC33200]
  3. National High Technology Program of China [2012AA022603]
  4. Doctoral Base Foundation of Educational Ministry of China [20120032110027]

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A smart pH-responsive photodynamic therapy system based on upconversion nanoparticle loaded PEG coated polymeric lipid vesicles (RB-UPPLVs) was designed and prepared. These RB-UPPLVs which are promising agents for deep cancer photodynamic therapy applications can achieve enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy.

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