The new International League Against Epilepsy (ILAE) definition of Lennox-Gastaut syndrome: Practical implications and limitations

Article Clinical Neurology

International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: Position paper by the ILAE Task Force on Nosology and Definitions

Nicola Specchio et al.

Summary: The 2017 International League Against Epilepsy classification defines a three-tier system for epilepsy syndromes, with childhood onset epilepsy syndromes falling into three categories: self-limited focal epilepsies, generalized epilepsies, and developmental and/or epileptic encephalopathies. Identification of specific syndromes helps guide management and prognosis. This paper describes these childhood onset epilepsy syndromes, highlighting their seizure types, EEG features, phenotypic variations, and key investigation findings.

EPILEPSIA (2022)

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Article Clinical Neurology

Age at onset in patients with Lennox-Gastaut syndrome: Correlations with clinical manifestations

Ali A. Asadi-Pooya et al.

Summary: The aim of this study was to investigate the age at onset in patients with Lennox-Gastaut Syndrome (LGS) and to explore the clinical and EEG characteristics of these patients in different age groups. The results showed that the age at onset of LGS has significant correlations with the clinical manifestations of the syndrome.

JOURNAL OF CLINICAL NEUROSCIENCE (2022)

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Article Clinical Neurology

Cluster analysis of a large dataset of patients with Lennox-Gastaut syndrome

Ali A. Asadi-Pooya et al.

Summary: The study identified three distinct clusters of patients with LGS using Two-Step cluster analysis, showing significant differences in seizure outcomes between these clusters.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2021)

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Article Clinical Neurology