Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 17, Pages 3641-3644Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc09120e
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Funding
- 973 Program [2013CB933800]
- National Natural Science Foundation of China [21304103, 51303191, 91027030, 21474123]
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A ratiometric, multifunctional nanoprobe was prepared consisting of a self-assembled polymeric micelle as the carrier, tetraphenylethene (TPE) as the donor, fluorescent boronate as the H2O2-responsive acceptor, and triphenylphosphonium as a mitochondria-targeted moiety. The assembled nanoparticles could detect both exogenous and endogenous mitochondrial H2O2 changes in living cells.
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