4.7 Article

Atomistic Molecular Insights into Angiotensin-(1-7) Interpeptide Interactions

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Peptide framework for screening the effects of amino acids on assembly

Seren Hamsici et al.

Summary: The discovery of a new strategy for studying peptide intermolecular interactions, based on co-assembly of oppositely charged peptides, is presented in this study. Computational and experimental methods were used to analyze the free energy and amino acid contacts during co-assembly, and their correlation with the physical properties of the aggregates. The results indicate that opposite charges and the presence of a hydrophobic core play crucial roles in the assembly of peptide-based materials.

SCIENCE ADVANCES (2022)

Article Biochemistry & Molecular Biology

Unveiling the G4-PAMAM capacity to bind and protect Ang-(1-7) bioactive peptide by molecular dynamics simulations

L. America Chi et al.

Summary: This study investigated the structural basis of the interaction between PAMAM dendrimers and Angiotensin-(1-7) peptide, as well as the effect of pH changes on their binding. The results showed that amino-terminated PAMAM dendrimer exhibited better features in terms of binding, loading, and protecting Angiotensin-(1-7) peptides.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2022)

Review Biochemistry & Molecular Biology

Therapeutic peptides: current applications and future directions

Lei Wang et al.

Summary: Peptide drug development has achieved significant progress in the past decade, thanks to new production, modification, and analytic technologies. These advancements have addressed the inherent limitations of peptides and have resulted in achievements in various therapeutic areas.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

Review Pharmacology & Pharmacy

Targeting the Protective Arm of the Renin-Angiotensin System: Focused on Angiotensin-(1-7)

Sana Khajehpour et al.

Summary: This article discusses the importance of the protective arm of the renin-angiotensin system and efforts to improve the stability and efficacy of Ang-(1-7) using novel drug delivery systems. By enhancing the protective arm, it may improve therapeutic outcomes for various diseases.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2021)

Article Chemistry, Physical

Modeling of Peptides with Classical and Novel Machine Learning Force Fields: A Comparison

David Rosenberger et al.

Summary: The replacement of classical force fields with neural-network-based frameworks is an emerging topic in molecular dynamics simulations. While machine learning potentials have yet to demonstrate their applicability for soft materials, the approach shows promise in learning the energy of atoms in their chemical environments. Comparing performance of the ANI-2x ML model with two classical force fields for bulk water and model peptides reveals potential for future improvements in ML potentials for simulations of soft matter systems.

JOURNAL OF PHYSICAL CHEMISTRY B (2021)

Article Chemistry, Multidisciplinary

Effect of monovalent salt concentration and peptide secondary structure in peptide-micelle binding

Suvankar Ghosh et al.

Summary: This research investigated the salt-sensitivity of the cationic 14 residue peptide LL-14 and the role of peptide secondary structure on its binding to membrane mimetics. LL-14 adopted an alpha-helical structure in SDS micelles, binding faster and deeper with increasing NaCl concentration. The electrostatics drove the initial binding of LL-14 to micelles, with cationic alpha-helical peptides being ideal for faster SDS binding.

RSC ADVANCES (2021)

Review Chemistry, Multidisciplinary

Peptide-Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration

Valentina Armiento et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Editorial Material Biochemical Research Methods

Promoting transparency and reproducibility in enhanced molecular simulations

Massimiliano Bonomi et al.

NATURE METHODS (2019)

Article Chemistry, Physical

Aggregation dynamics of charged peptides in water: Effect of salt concentration

Susmita Ghosh et al.

JOURNAL OF CHEMICAL PHYSICS (2019)

Article Biochemistry & Molecular Biology

Stabilization of Angiotensin-(1-7) in Cardioprotective Solutions

Miriam Russ et al.

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2019)

Article Chemistry, Physical

Effects of All-Atom Molecular Mechanics Force Fields on Amyloid Peptide Assembly: The Case of Aβ16-22 Dimer

Viet Hoang Man et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2019)

Article Biochemistry & Molecular Biology

Therapeutic peptides: Historical perspectives, current development trends, and future directions

Jolene L. Lau et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2018)

Review Food Science & Technology

Current trends and perspectives of bioactive peptides

Eric Banan-Mwine Daliri et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2018)

Article Nanoscience & Nanotechnology

The complex of PAMAM-OH dendrimer with Angiotensin (1-7) prevented the disuse-induced skeletal muscle atrophy in mice

Valeria Marquez-Miranda et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

Article Multidisciplinary Sciences

Mineral surface chemistry control for origin of prebiotic peptides

Valentina Erastova et al.

NATURE COMMUNICATIONS (2017)

Article Biology

Factors affecting the physical stability (aggregation) of peptide therapeutics

Karolina L. Zapadka et al.

INTERFACE FOCUS (2017)

Article Chemistry, Physical

A GROMOS-Compatible Force Field for Small Organic Molecules in the Condensed Phase: The 2016H66 Parameter Set

Bruno A. C. Horta et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2016)

Article Biochemistry & Molecular Biology

Pep-Calc.com: a set of web utilities for the calculation of peptide and peptoid properties and automatic mass spectral peak assignment

Sam Lear et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2016)

Review Pharmacology & Pharmacy

Peptide therapeutics: current status and future directions

Keld Fosgerau et al.

DRUG DISCOVERY TODAY (2015)

Article Computer Science, Interdisciplinary Applications

PLUMED 2: New feathers for an old bird

Gareth A. Tribello et al.

COMPUTER PHYSICS COMMUNICATIONS (2014)

Article Biophysics

Graphical analysis of pH-dependent properties of proteins predicted using PROPKA

Michal Rostkowski et al.

BMC STRUCTURAL BIOLOGY (2011)

Article Computer Science, Interdisciplinary Applications

PLUMED: A portable plugin for free-energy calculations with molecular dynamics

Massimiliano Bonomi et al.

COMPUTER PHYSICS COMMUNICATIONS (2009)

Article Biotechnology & Applied Microbiology

Hofmeister effects: an explanation for the impact of ionic liquids on biocatalysis

Zhen Yang

JOURNAL OF BIOTECHNOLOGY (2009)

Article Chemistry, Physical

Computer Simulations of Peptides from the p53 DNA Binding Domain

Mey Khalili et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)

Review Chemistry, Multidisciplinary

CHARMM: The Biomolecular Simulation Program

B. R. Brooks et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)

Article Biophysics

Peptide aggregation in finite systems

Gurpreet Singh et al.

BIOPHYSICAL JOURNAL (2008)

Review Pharmacology & Pharmacy

Angiotensin-(1-7): Pharmacological properties and pharmacotherapeutic perspectives

Dilek Iusuf et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

Article Physics, Multidisciplinary

Reentrant condensation of proteins in solution induced by multivalent counterions

F. Zhang et al.

PHYSICAL REVIEW LETTERS (2008)

Article Chemistry, Physical

Canonical sampling through velocity rescaling

Giovanni Bussi et al.

JOURNAL OF CHEMICAL PHYSICS (2007)

Article Biochemistry & Molecular Biology

pH-dependent aggregate forms and conformation of Alzheimer amyloid β-peptide (12-24)

H Abe et al.

JOURNAL OF BIOCHEMISTRY (2002)