4.5 Article

Controllable Preparation of Monodisperse Chitosan Microspheres Based on Microfluidic Technology

Journal

JOURNAL OF CHEMICAL EDUCATION
Volume -, Issue -, Pages -

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.jchemed.2c00901

Keywords

Microfluidics; Droplet Microfluidics; LaboratoryExperiment; Chitosan Microspheres; PDMS

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This experiment is designed for undergraduate students to introduce droplet microfluidics. Through this experiment, students can understand the concept of microfluidic channels and the principles of droplet microfluidics, prepare PDMS devices and split-flow strategy, explore the controllable preparation and monodispersity of chitosan microspheres, and gain a more comprehensive understanding of microfluidic technology. The experiment is easy to operate and has a short cycle, making it suitable as an undergraduate experiment.
Previous educational articles on microfluidic technology mainly focused on continuous microfluidics, so we set up an undergraduate laboratory experiment to introduce droplet microfluidics to students. Students can understand the concept of microfluidic channels and the principles of droplet microfluidics, prepare polydimethylsiloxane (PDMS) devices and split-flow strategy, explore the controllable preparation and monodispersity of chitosan (CS) microspheres, and gain a more comprehensive understanding of microfluidic technology. The experiment has the advantages of easy operation and a short cycle, and it is suitable as an undergraduate experiment.

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