4.4 Article Proceedings Paper

PMMA microfluidic chip fabrication using laser ablation and low temperature bonding with OCA film and LOCA

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00542-016-2924-1

Keywords

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Funding

  1. National Natural Science Foundation of China [21105076, 81372358, 51303140, 51302196]
  2. Foundation of Education Bureau of Hubei Province, China [D20121705]
  3. Science Technology Foundation of Hubei Province, China [2011BAB038]
  4. Natural Science Foundation of Hubei Province, China [2014CF029]
  5. Colleges of Hubei Province Outstanding Youth Science and Technology Innovation Team [T201305]

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A new PMMA microfluidic chip fabrication method by combining laser ablation technology with low-temperature bonding using optically clear adhesive (OCA) film and liquid optically clear adhesive (LOCA) was presented in this paper. The deformation and clogging issues of the microfluidic channel were well solved. The effective bonding area ratio of microfluidic chips could be greatly improved by adjusting bonding temperature and bonding time. The crevices around the microchannels were effectively eliminated by coating treatment of LOCA. The bonding strength and waterproof of PMMA microfluidic chips coating with/without LOCA were also evaluated in this paper.

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