4.7 Article

Nickel-catalyzed and benzoic acid-promoted direct sulfenylation of unactivated arenes

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 17, Pages 3582-3585

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc10431e

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Funding

  1. National Natural Science Foundation of China [21332005, 21372115, 21472085]
  2. Natural Science Foundation of Jiangsu Province [BK2012012, BK20131267]
  3. Qing Lan Project
  4. Deanship of Scientific Research at King Saud University [RGP VPP-207]

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A nickel-catalyzed and benzoic acid-promoted direct sulfenylation of unactivated arenes using removable 2-(pyridine-2-yl)-isopropylamine as a directing group is described. This strategy provides an efficient access to valuable aryl sulfides with ample substrate scope and a high degree of functional group tolerance.

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