Toxicology and safety study of L-tryptophan and its impurities for use in broiler feed

Article Biochemistry & Molecular Biology

Simultaneous determination of l-tryptophan impurities in meat products

Doo-Hee Lee et al.

Summary: This study aims to develop an analytical method for the simultaneous detection of l-tryptophan impurities in meat products using LC-MS/MS. Detection methods for (S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid (5-hydroxytryptophan) (HTP), 1-methyl-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid (MTCA), 3a-hydroxy-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]-indole-2-carboxylic acid (PIC), and 1,1'-ethylidenebistryptophan (EBT) and 2-(3-indoylmethyl)-l-tryptophan (IMT) were developed. The developed method allowed simultaneous determination of these four impurities in 5 min. No interferences from the matrix were observed, and the method showed good sensitivity to each analyte. The method detection limit and limit of quantification in meat matrices were below 11.2 and 35.7 mu g/kg, respectively.

AMINO ACIDS (2023)

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Article Agriculture, Dairy & Animal Science

Ways to minimize bacterial infections, with special reference to Escherichia coli, to cope with the first-week mortality in chicks: an updated overview

Ayman A. Swelum et al.

Summary: The article discusses the impact of poultry infections on the commercial poultry industry, focusing on the mortality and disease symptoms caused by E. coli infections in neonatal poultry. It also highlights the use of prophylactic antibiotics and the search for alternative solutions due to consumer demand for reduced antibiotic-resistant bacteria.

POULTRY SCIENCE (2021)

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Article Agriculture, Dairy & Animal Science