4.7 Article

Amide-triazole isosteric substitution for tuning self-assembly and incorporating new functions into soft supramolecular materials

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 25, Pages 5294-5297

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc08593k

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Funding

  1. DFG [DI 1748/3-1]
  2. Universitat Regensburg, Ministerio de Economia y Competitividad-FEDER [CTQ2010-17436, CTQ2013-40855-R]
  3. Gobierno de Aragon-FSE [E40]

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The proof-of-concept for the modular synthesis of new functional soft gel materials based on amide-triazole isosteric replacement has been demonstrated. A coassembly approach of isosteric amino acid-based hydrogelators was fruitfully applied for fine-tuning the release of entrapped drugs.

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