Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 87, Pages 15752-15755Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc06767g
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Funding
- Deutsche Forschungsgemeinschaft (DFG) [SFB 1032]
- DFG [WU 622/4-1]
- Excellence Cluster Nanosystems Initiative Munich (NIM)
- Center for NanoScience Munich (CeNS)
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We report the synthesis of MOF@lipid nanoparticles as a versatile and powerful novel class of nanocarriers based on metal- organic frameworks (MOFs). We show that the MOF@lipid system can effectively store dye molecules inside the porous scaffold of the MOF while the lipid bilayer prevents their premature release. Efficient uptake of the MOF@lipid nanoparticles by cancer cells makes these nanocarriers promising for drug delivery and diagnostic purposes.
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