4.7 Letter

Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations

Related references

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Article Hematology

Graft rejection markers in children undergoing hematopoietic cell transplant for bone marrow failure

Anthony Sabulski et al.

Summary: The study identified higher levels of CXCL9, BAFF, and sC5b-9 in patients with GR compared to HCT controls. Patients with GR experienced significantly higher and later fevers in the transplant course. This suggests potential for using interferon, complement, and BAFF inhibitors as therapies for preventing and treating GR after HCT.

BLOOD ADVANCES (2021)