Monitoring of Volatile Additives from Plant Protection Products in Tomatoes Using HS-SPME-GC-HRMS: Targeted and Suspect Approaches

Article Medicine, Legal

Health safety of parabens evaluated by selected in vitro methods

L. Svobodova et al.

Summary: This study confirmed the safety of using the allowed parabens in the highest recommended concentrations in cosmetics or pharmaceuticals, based on testing their toxicological properties using novel in vitro methods.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2023)

Add to Collection

Article Agriculture, Multidisciplinary

Uncovering the Dissipation of Chlorantraniliprole in Tomatoes: Identifying Transformation Products (TPs) and Coformulants in Greenhouse and Laboratory Studies by UHPLC-Q-Orbitrap-MS and GC-Q-Orbitrap-MS

Antonio Jesus Maldonado-Reina et al.

Summary: The dissipation of chlorantraniliprole insecticide in tomatoes treated with Altacor 35 WG was studied in laboratory and greenhouse conditions, and suspect screening analysis was performed to identify transformation products and coformulants. Analyses using UHPLC-Q-Orbitrap-MS and GC-Q-Orbitrap-MS showed that chlorantraniliprole followed a biphasic kinetic model with R2 values greater than 0.99. Dissipation was faster in greenhouse studies, with 96% achieved over 53 days. One transformation product (IN-F6L99) was tentatively identified in both laboratory and greenhouse studies, and 15 volatile coformulants were identified by GC-Q-Orbitrap-MS.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2023)

Add to Collection

Article Chemistry, Analytical

Unravelling plant protection product analysis: Use of chromatography techniques (GC and LC) and high resolution mass spectrometry

Rosalia Lopez-Ruiz et al.

Summary: This study proposes a methodology for characterizing plant protection products (PPPs) through suspect and unknown analyses. It involves three main stages: sample preparation, separation and detection, and data analysis. The use of different solvents and chromatographic techniques, such as LC and GC coupled with HRMS analyzers, allows for accurate detection and a high number of features. Tips and recommendations for data analysis are provided to perform suspect screening and unknown analysis.

TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY (2023)

Add to Collection

Article Agriculture, Multidisciplinary

Looking beyond the Active Substance: Comprehensive Dissipation Study of Myclobutanil-Based Plant Protection Products in Tomatoes and Grapes Using Chromatographic Techniques Coupled to High-Resolution Mass Spectrometry

Jesus Marin-Saez et al.

Summary: A comprehensive evaluation of myclobutanil dissipation in tomato and grape samples was conducted, with a biphasic kinetic model providing a suitable adjustment. Six myclobutanil metabolites were identified, four of which were described for the first time. The degradation curves of the metabolites and the coformulants present in the commercial formulation were studied.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022)

Add to Collection

Article Agriculture, Multidisciplinary

Characterization of the composition of plant protection products in different formulation types employing suspect screening and unknown approaches

Maria Elena Hergueta-Castillo et al.

Summary: The study successfully characterized the composition of six different PPPs using UHPLC coupled to a Quadrupole-Orbitrap mass analyzer. These PPPs had antifungal activity, containing one triazole compound as active principle.

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2022)

Add to Collection

Article Biochemical Research Methods

Non-targeted analysis of co-formulants in antifungal pesticide formulations by gas chromatography-tandem high resolution mass spectrometry

Maria Elena Hergueta-Castillo et al.

Summary: In this study, six commercial pesticide formulations with antifungal activity were characterized and identified using two complementary injection methods based on gas chromatography coupled to high resolution mass spectrometry. The results showed that the methodology was suitable for the reliable identification of co-formulants in pesticide formulations, and several co-formulants with similar molecular formula were successfully differentiated. The detected co-formulants were found to have toxicity to human health and the environment.

JOURNAL OF CHROMATOGRAPHY A (2022)

Add to Collection

Article Agriculture, Multidisciplinary

Assessment of Co-Formulants in Marketed Plant Protection Products by LC-Q-Orbitrap-MS: Application of a Hybrid Data Treatment Strategy Combining Suspect Screening and Unknown Analysis

Antonio Jesus Maldonado-Reina et al.

Summary: This study aimed to identify co-formulants in 15 different plant protection products (PPPs) with chlorantraniliprole and difenoconazole. A total of 78 co-formulants were tentatively identified and 9 were confirmed. Linear alkyl ethoxylates (LAS) were the most common type of co-formulant, followed by sodium alkylbenzene sulfonates. This innovative identification method will contribute to future research on the composition of PPPs and the determination of these co-formulants in environmental or agricultural samples.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2022)

Add to Collection

Review Environmental Sciences

Biopesticides and insect pollinators: Detrimental effects, outdated guidelines, and future directions

Federico Cappa et al.

Summary: Biopesticides are gaining attention as a sustainable alternative to synthetic pesticides, but there is limited research on their potential negative effects on pollinators. Current risk assessment methods are insufficient to evaluate all possible side-effects, highlighting the need for more comprehensive studies in this field.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Add to Collection

Article Agronomy

Magnitude and decline of pesticide co-formulant residues in vegetables and fruits: results from field trials compared to estimated values

Marianne E. Balmer et al.

Summary: The application of plant protection products leads to residue formation in crops, with co-formulants detected at high levels but declining rapidly. Removal processes such as wash-off and volatilization play important roles in reducing residues, although organic solvent residues remain considerable in specific crops even after two weeks. Estimation of co-formulant residues using publicly available data on pesticide a.s. is feasible, providing important insights for future considerations of consumer exposure.

PEST MANAGEMENT SCIENCE (2021)

Add to Collection

Article Chemistry, Analytical

Co-formulants in plant protection products: An analytical approach to their determination by gas chromatography-high resolution mass accuracy spectrometry

Antonio Jesus Maldonado-Reina et al.

Summary: The study identified 12 volatile benzene and naphthalene derived co-formulants in plant protection products using gas chromatography coupled to high resolution mass accuracy spectrometry, successfully detecting these compounds at concentrations as low as 0.03 g/L. The applied methodology demonstrated efficient separation and detection of the compounds, with pentamethylbenzene being the only compound detected in all samples.

TALANTA (2021)

Add to Collection

Article Biochemical Research Methods