Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 56, Pages 11260-11263Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc03162a
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Funding
- National Science Foundation [DMR-1148836, DMR-1206219]
- National Institutes of Health [R01AR064200, R01DE022949, P30AI078498]
- Division Of Materials Research
- Direct For Mathematical & Physical Scien [1148836] Funding Source: National Science Foundation
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Fmoc-3F-Phe-Arg-NH2 and Fmoc-3F-Phe-Asp-OH dipeptides undergo coassembly to form two-component nanofibril hydrogels. These hydrogels support the viability and growth of NIH 3T3 fibroblast cells. The supramolecular display of Arg and Asp at the nanofibril surface effectively mimics the integrin-binding RGD peptide of fibronectin, without covalent connection between the Arg and Asp functionality.
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