4.7 Article

Peptide-catalyzed, bioinspired silicification for single-cell encapsulation in the imidazole-buffered system

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 25, Pages 5523-5525

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc08544b

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Funding

  1. National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning (MSIP) [2013R1A1A1008102, 2012R1A3A2026403, 20090083525]

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Inspired by biosilicification of glass sponges, we designed a catalytic peptide, which formed silica structures in the imidazole-buffered solution. The peptide was adsorbed selectively onto the surface of yeast cells, and the bioinspired silicification led to the formation of a cytoprotective silica shell on individual yeast cells.

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