Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 46, Pages 9567-9570Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc02149a
Keywords
-
Categories
Funding
- NSFC [21474031, 21174040, 21025415]
- National Key Basic Research Program of China [2013CB834702]
Ask authors/readers for more resources
A DT-diaphorase-activatable theranostic prodrug, which contains camptothecin, a self-immolative linker and a trigger group, has been developed for the detection of DT-diaphorase, tracking of drug release and selectively killing cancer cells over-expressed with DT-diaphorase. This strategy may offer a new approach for the development of enzyme-catalyzed theranostic anticancer therapeutics.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available