4.4 Review

Overview of chemical imaging methods to address biological questions

Journal

MICRON
Volume 84, Issue -, Pages 23-36

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micron.2016.02.005

Keywords

STEM; EELS; EFTEM; NanoSIMS; PIXE; Synchrotron radiation micro-analysis

Categories

Funding

  1. Agence Nationale pour la Recherche (ANR) program PIRIBIO [ANR-09-PIRI-0029-01]
  2. Fundacao de Amparo a Pesquisa Carlos Chagas Filho - FAPERJ
  3. Conselho Nacional de Pesquisa - CNPq, Brazil
  4. [ANR-11-BSV8-016]
  5. Agence Nationale de la Recherche (ANR) [ANR-09-PIRI-0029] Funding Source: Agence Nationale de la Recherche (ANR)

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Chemical imaging offers extensive possibilities for better understanding of biological systems by allowing the identification of chemical components at the tissue, cellular, and subcellular levels. In this review, we introduce modern methods for chemical imaging that can be applied to biological samples. This work is mainly addressed to the biological sciences community and includes the bases of different technologies, some examples of its application, as well as an introduction to approaches on combining multimodal data. (C) 2016 The Authors. Published by Elsevier Ltd.

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