Related references
Note: Only part of the references are listed.New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2
Rebecca Ferrisi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Microglial large extracellular vesicles propagate early synaptic dysfunction in Alzheimer's disease
Martina Gabrielli et al.
BRAIN (2022)
Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy
Chao Wang et al.
NATURE COMMUNICATIONS (2022)
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands
Francesca Gado et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Microglia and Alzheimer's Disease
Stefania Merighi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
The regulatory role of AP-2β in monoaminergic neurotransmitter systems: insights on its signalling pathway, linked disorders and theragnostic potential
Mohamed H. Al-Sabri et al.
CELL AND BIOSCIENCE (2022)
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R)
Rebecca Ferrisi et al.
FRONTIERS IN CHEMISTRY (2022)
Trace Amine-Associated Receptor 1 (TAAR1): Molecular and Clinical Insights for the Treatment of Schizophrenia and Related Comorbidities
Pramod C. Nair et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2022)
The 3-iodothyronamine (T1AM) and the 3-iodothyroacetic acid (TA1) indicate a novel connection with the histamine system for neuroprotection
Annunziatina Laurino et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2021)
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
Fangda Leng et al.
NATURE REVIEWS NEUROLOGY (2021)
TAAR1 Expression in Human Macrophages and Brain Tissue: A Potential Novel Facet of MS Neuroinflammation
David A. Barnes et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Targeting innate immunity to protect and cure Alzheimer's disease: opportunities and pitfalls
Giulia Cisbani et al.
MOLECULAR PSYCHIATRY (2021)
Delivery of Thyronamines (TAMs) to the Brain: A Preliminary Study
Nicoletta di Leo et al.
MOLECULES (2021)
T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex
Francesca Tozzi et al.
NEUROBIOLOGY OF DISEASE (2021)
Microglial functional alteration and increased diversity in the challenged brain: Insights into novel targets for intervention
Marie-Eve Tremblay
BRAIN, BEHAVIOR, & IMMUNITY - HEALTH (2021)
Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-Like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents through the Modulation of SIRT6
Lorenza Bellusci et al.
MOLECULES (2020)
Exogenous 3-Iodothyronamine Rescues the Entorhinal Cortex from β-Amyloid Toxicity
Alice Accorroni et al.
THYROID (2020)
A Non-D2-Receptor-Binding Drug for the Treatment of Schizophrenia
Kenneth S. Koblan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
Microglia-mediated neuroinflammation in neurodegenerative diseases
Charannya Sozheesvari Subhramanyam et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2019)
N-(3-Ethoxy-phenyl)-4-pyrrolidin-1-yl-3-trifluoromethyl-benzamide (EPPTB) prevents 3-iodothyronamine (T1AM)-induced neuroprotection against kainic acid toxicity
Elisa Landucci et al.
NEUROCHEMISTRY INTERNATIONAL (2019)
Methamphetamine decreases K+ channel function in human fetal astrocytes by activating the trace amine-associated receptor type-1
Sonya Dave et al.
JOURNAL OF NEUROCHEMISTRY (2019)
Trace amine-associated receptor 1: a multimodal therapeutic target for neuropsychiatric diseases
Michael D. Schwartz et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2018)
Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression
Fariba M. Assadi-Porter et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Neurodegenerative diseases
Wolfgang Reith
RADIOLOGE (2018)
The Case for TAAR1 as a Modulator of Central Nervous System Function
Grazia Rutigliano et al.
FRONTIERS IN PHARMACOLOGY (2018)
Trace Amine-Associated Receptors as Novel Therapeutic Targets for Immunomodulatory Disorders
Sherri L. Christian et al.
FRONTIERS IN PHARMACOLOGY (2018)
Review and Meta-Analyses of TAAR1 Expression in the Immune System and Cancers
Lisa M. Fleischer et al.
FRONTIERS IN PHARMACOLOGY (2018)
Central effects of 3-Iodothyronamine Reveal a novel Role for Mitochondrial Monoamine Oxidases
Annunziatina Laurino et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
The human microglial HMC3 cell line: where do we stand? A systematic literature review
Cinzia Dello Russo et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Low-grade inflammation in the relationship between sleep disruption, dysfunctional adiposity, and cognitive decline in aging
Mercedes Atienza et al.
SLEEP MEDICINE REVIEWS (2018)
Microglia and macrophages in brain homeostasis and disease
Qingyun Li et al.
NATURE REVIEWS IMMUNOLOGY (2018)
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection
Lorenza Bellusci et al.
FRONTIERS IN PHARMACOLOGY (2017)
Trace amine-associated receptor 1 agonists RO5263397 and RO5166017 attenuate quinpirole-induced yawning but not hypothermia in rats
Justin N. Siemian et al.
BEHAVIOURAL PHARMACOLOGY (2017)
Microglia-Mediated Inflammation and Neurodegenerative Disease
Ling Xu et al.
MOLECULAR NEUROBIOLOGY (2016)
Gx-50 reduces β-amyloid-induced TNF-α, IL-1β, NO, and PGE2 expression and inhibits NF-κB signaling in a mouse model of Alzheimer's disease
Shi Shi et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
Role of neuroinflammation in neurodegenerative diseases
Wei-Wei Chen et al.
MOLECULAR MEDICINE REPORTS (2016)
Endocannabinoids drive the acquisition of an alternative phenotype in microglia
M. Mecha et al.
BRAIN BEHAVIOR AND IMMUNITY (2015)
In the brain of mice, 3-iodothyronamine (T1AM) is converted into 3-iodothyroacetic acid (TA1) and it is included within the signaling network connecting thyroid hormone metabolites with histamine
Annunziatina Laurino et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2015)
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists
Grazia Chiellini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Histamine mediates behavioural and metabolic effects of 3-iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism
Claudia Musilli et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Uptake and metabolic effects of 3-iodothyronamine in hepatocytes
Sandra Ghelardoni et al.
JOURNAL OF ENDOCRINOLOGY (2014)
Methamphetamine and HIV-1-induced neurotoxicity: Role of trace amine associated receptor 1 cAMP signaling in astrocytes
Irma E. Cisneros et al.
NEUROPHARMACOLOGY (2014)
Calcium dysregulation and neuroinflammation: Discrete and integrated mechanisms for age-related synaptic dysfunction
Diana M. Sama et al.
AGEING RESEARCH REVIEWS (2013)
Self-propagation of pathogenic protein aggregates in neurodegenerative diseases
Mathias Jucker et al.
NATURE (2013)
Amyloid β-Peptide 25-35 Self-Assembly and Its Inhibition: A Model Undecapeptide System to Gain Atomistic and Secondary Structure Details of the Alzheimer's Disease Process and Treatment
Marina Naldi et al.
ACS CHEMICAL NEUROSCIENCE (2012)
TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity
Florent G. Revel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mechanisms Underlying Inflammation in Neurodegeneration
Christopher K. Glass et al.
CELL (2010)
Tissue Distribution and Cardiac Metabolism of 3-Iodothyronamine
Alessandro Saba et al.
ENDOCRINOLOGY (2010)
Hydrogen Sulfide Protects Amyloid-beta Induced Cell Toxicity in Microglia
Yan-Ying Liu et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Microglial Activation and Chronic Neurodegeneration
Melinda E. Lull et al.
NEUROTHERAPEUTICS (2010)
Trace amine-associated receptor 1 as a monoaminergic modulator in brain
Zhihua Xie et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity
Jianfeng Liang et al.
BRAIN RESEARCH (2008)
Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor
Larry S. Barak et al.
MOLECULAR PHARMACOLOGY (2008)
Trace amine-associated receptor 1 modulates dopaminergic activity
Lothar Lindemann et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Exploring the full spectrum of macrophage activation
David M. Mosser et al.
NATURE REVIEWS IMMUNOLOGY (2008)
Microglial activation and its implications in the brain diseases
S. Thameem Dheen et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Glia as a therapeutic target:: Selective suppression of human amyloid-β-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration
HR Ranaivo et al.
JOURNAL OF NEUROSCIENCE (2006)
3-iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone
TS Scanlan et al.
NATURE MEDICINE (2004)
Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1β on long term potentiation in rat dentate gyrus
A Kelly et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity
D Pubill et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2003)
Chronic brain inflammation results in cell loss in the entorhinal cortex and impaired LTP in perforant path-granule cell synapses
B Hauss-Wegrzyniak et al.
EXPERIMENTAL NEUROLOGY (2002)
NF-κB in neuronal plasticity and neurodegenerative disorders
MP Mattson et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Inflammation and Alzheimer's disease
H Akiyama et al.
NEUROBIOLOGY OF AGING (2000)
Cell mediators of inflammation in the Alzheimer disease brain
H Akiyama et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2000)