Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 41, Pages 8588-8591Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4cc09595b
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Conducting organic syntheses in microfluidic chips allows studying and optimising chemical reactions at minimal time-scales and resource consumption. Herein, we describe a multi-channel micro-droplet chip, which allows fast and directed dispensing of reactants into individual droplets in a segmented flow. This gives access to study the reaction progress in situ via surface-enhanced Raman spectroscopic monitoring of fast moving individual droplets. This opens up new avenues for high-throughput screening of organic reactions at the micro-and nano-scale.
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