4.7 Article

Developmental Neurotoxicity of Trichlorfon in Zebrafish Larvae

Related references

Note: Only part of the references are listed.
Article Fisheries

Trichlorfon exposure in common carp (Cyprinus carpio L.) leads to oxidative stress, neurotoxicity, and immune responses

Xianfeng Wang et al.

Summary: The study revealed that trichlorfon induced more severe oxidative stresses in the liver than in the brain of common carp, potentially leading to neurotoxicity and affecting immune responses. In addition, neurotransmitter contents were reduced in the brain, while inflammatory cytokines increased in response to trichlorfon exposure. Histological observations also showed changes in melano-macrophage centers in the head kidney and spleen of exposed carp.

AQUACULTURE (2022)

Article Agriculture, Dairy & Animal Science

A Perspective of Molecular Cytogenomics, Toxicology, and Epigenetics for the Increase of Heterochromatic Regions and Retrotransposable Elements in Tambaqui (Colossoma macropomum) Exposed to the Parasiticide Trichlorfon

Maria dos Santos Costa et al.

Summary: The study evaluated the effects of Trichlorfon on retrotransposable elements in the genome of Colossoma macropomum. The results showed that Trichlorfon activates the retrotransposable elements, particularly Rex3. These elements were found to be dispersed in the chromosomes of Colossoma macropomum, and Trichlorfon enhanced chromosomal heterochromatinization. This behavior was most prominent at higher Trichlorfon concentrations and exposure times, indicating genetic flexibility for environmental adaptation.

ANIMALS (2022)

Article Geriatrics & Gerontology

Different Exercise Time on 5-HT and Anxiety-like Behavior in the Rat With Vascular Dementia

Yongzhao Fan et al.

Summary: This study investigated the effects of different pre-vascular-dementia exercise times on anxiety-like behavior and hippocampal 5-HT levels in rats. The results showed that both 1 week and 4 weeks of voluntary wheel running exercise can inhibit anxiety-like behavior in rats with vascular dementia by upregulating hippocampal 5-HT levels.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2022)

Article Environmental Sciences

Glyphosate targets fish monoaminergic systems leading to oxidative stress and anxiety

Melissa Faria et al.

Summary: Glyphosate, the active ingredient in many herbicides, has been found to have neurotoxic effects, including increased anxiety and altered social behaviors in adult zebrafish exposed to environmentally relevant concentrations. Changes in neurotransmitter levels and antioxidant defense systems were observed in the brains of exposed fish, suggesting potential negative impacts on fish survival and human health from chronic low-dose exposures commonly found in aquatic ecosystems.

ENVIRONMENT INTERNATIONAL (2021)

Article Environmental Sciences

Bioconcentration and developmental neurotoxicity of novel brominated flame retardants, hexabromobenzene and pentabromobenzene in zebrafish

Xiangping Chen et al.

Summary: In this study, the flame retardants hexabromobenzene (HBB) and pentabromobenzene (PBB) were found to exhibit developmental neurotoxicity in zebrafish larvae, affecting parameters related to central nervous system development. However, they did not cause developmental toxicity. These findings provide important insights for future toxicological research and risk assessment of novel brominated flame retardants.

ENVIRONMENTAL POLLUTION (2021)

Article Engineering, Environmental

In vitro biolayer interferometry analysis of acetylcholinesterase as a potential target of aryl-organophosphorus flame-retardants

Qipeng Shi et al.

Summary: The study revealed that aryl-OPFRs can act as potent AChE inhibitors, and may therefore present a significant ecological risk to aquatic organisms.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Article Environmental Sciences

Dichlorvos alters morphology and behavior in zebrafish (Danio rerio) larvae

Stefani Altenhofen et al.

ENVIRONMENTAL POLLUTION (2019)

Review Physiology

Serotonin transport in the 21st century

Gary Rudnick et al.

JOURNAL OF GENERAL PHYSIOLOGY (2019)

Article Multidisciplinary Sciences

Generation of a whole-brain atlas for the cholinergic system and mesoscopic projectome analysis of basal forebrain cholinergic neurons

Xiangning Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Engineering, Environmental

Acetylcholinesterase Is a Potential Biomarker for a Broad Spectrum of Organic Environmental Pollutants

Hualing Fu et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2018)

Article Marine & Freshwater Biology

Developmental neurotoxicity of triphenyl phosphate in zebrafish larvae

Qipeng Shi et al.

AQUATIC TOXICOLOGY (2018)

Article Pharmacology & Pharmacy

New insights on molecular interactions of organophosphorus pesticides with esterases

Iris Mangas et al.

TOXICOLOGY (2017)

Article Engineering, Environmental

Changes in Neurotransmitter Profiles during Early Zebrafish (Danio rerio) Development and after Pesticide Exposure

Sara Tufi et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2016)

Article Environmental Sciences

THE DEVELOPMENTAL NEUROTOXICITY OF POLYBROMINATED DIPHENYL ETHERS: EFFECT OF DE-71 ON DOPAMINE IN ZEBRAFISH LARVAE

Xianfeng Wang et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2015)

Article Pharmacology & Pharmacy

Developmental neurotoxic effects of two pesticides: Behavior and biomolecular studies on chlorpyrifos and carbaryl

Iwa Lee et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2015)

Review Clinical Neurology

Neurobehavioural effects of developmental toxicity

Philippe Grandjean et al.

LANCET NEUROLOGY (2014)

Article Behavioral Sciences

Acute administration of dopaminergic drugs has differential effects on locomotion in larval zebrafish

T. D. Irons et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2013)

Article Engineering, Environmental

Prenatal Transfer of Polybrominated Diphenyl Ethers (PBDEs) Results in Developmental Neurotoxicity in Zebrafish Larvae

Lianguo Chen et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2012)

Article Fisheries

Effect of Trichlorfon on Hepatic Lipid Accumulation in Crucian Carp Carassius auratus gibelio

WeiNa Xu et al.

JOURNAL OF AQUATIC ANIMAL HEALTH (2012)

Review Biochemistry & Molecular Biology

Alteration of serotonin system by polychlorinated biphenyls exposure

Jordi Boix et al.

NEUROCHEMISTRY INTERNATIONAL (2012)

Article Marine & Freshwater Biology

Assessing lethal and sub-lethal effects of trichlorfon on different trophic levels

Sonia Coelho et al.

AQUATIC TOXICOLOGY (2011)

Article Biochemistry & Molecular Biology

Swimming impairment and acetylcholinesterase inhibition in zebrafish exposed to copper or chlorpyrifos separately, or as mixtures

Fred A. Tilton et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY (2011)

Article Neurosciences

Zebrafish neurotransmitter systems as potential pharmacological and toxicological targets

E. P. Rico et al.

NEUROTOXICOLOGY AND TERATOLOGY (2011)

Article Environmental Sciences

The effect of trichlorfon on acetylcholinesterase activity and histopathology of cultivated fish Oreochromis niloticus

A. T. B. Guimaraes et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2007)

Review Neurosciences

Dopamine: 50 years in perspective

Susan D. Iversen et al.

TRENDS IN NEUROSCIENCES (2007)

Review Gastroenterology & Hepatology

The serotonin signaling system: From basic understanding to drug development-for functional GI disorders

Michael D. Gershon et al.

GASTROENTEROLOGY (2007)

Article Environmental Sciences

Bioconcentration of trichlorfon insecticide in pacu (Piaractus mesopotamicus)

Ruy Bessa Lopes et al.

CHEMOSPHERE (2006)

Article Medicine, General & Internal

Characterization and expression of serotonin transporter genes in zebrafish

YH Wang et al.

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2006)

Meeting Abstract Biochemistry & Molecular Biology

Expression of acetylcholinesterase (AChE) and aryl acylamidase (AAA) during early zebrafish embryogenesis

KV Allebrandt et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2005)

Review Neurosciences

Dopamine, learning and motivation

RA Wise

NATURE REVIEWS NEUROSCIENCE (2004)

Article Neurosciences

Characterization of myelination in the developing zebrafish

C Brösamle et al.