Stem Cell Therapy in Children with Traumatic Brain Injury

Pediatric traumatic brain injury is a cause of major mortality, and resultant neurological sequelae areassociated with long-term morbidity. Increasing studies have revealed stem cell therapy to be a potential new treatment. However, much work is still required to clarify the mechanism of action of effective stem cell therapy, type of stem cell therapy, optimal timing of therapy initiation, combination of cocurrent medical treatment and patient selection criteria. This paper will focus on stem cell therapy in children with traumatic brain injury.

Automated summary

Pediatric traumatic brain injury is a significant cause of mortality, and stem cell therapy has emerged as a potential treatment option. However, further research is needed to understand the mechanisms, types, optimal timing, combination with concurrent medical treatment, and patient selection criteria of effective stem cell therapy.