☆ 4.7 Article

Changes in Melatonin Concentration in a Clinical Observation Study under the Influence of Low-Frequency Magnetic Fields (Magnetic Stimulation in Men with Low Back Pain)-Results of Changes in an Eight-Point Circadian Profile

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Related references

Note: Only part of the references are listed.

Review Biochemistry & Molecular Biology

Melatonin Can Modulate Neurodegenerative Diseases by Regulating Endoplasmic Reticulum Stress

Yeong-Min Yoo et al.

Summary: As people age, their risks of developing degenerative diseases such as cancer, diabetes, Parkinson's Disease (PD), Alzheimer's Disease (AD), rheumatoid arthritis, and osteoporosis increase. Neurodegenerative diseases are recognized as the leading cause of affliction in the elderly worldwide. Research suggests that endoplasmic reticulum (ER) stress is associated with some neurological diseases like PD and AD. Melatonin, a hormone synthesized in the pineal gland, has various biological functions including circadian rhythm control, immune enhancement, and antioxidant, anti-aging, and anti-tumor effects. This paper aims to summarize the effects of melatonin on neurons and neurodegenerative diseases related to ER stress, highlighting its role in protecting neurons and treating neurodegeneration.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection

Article Biochemistry & Molecular Biology

Role of melatonin receptor 1B gene polymorphism and its effect on the regulation of glucose transport in gestational diabetes mellitus

Lijie Wei et al.

Summary: This study investigated the relationship between the rs10830963 variant and gestational diabetes mellitus (GDM) development, as well as the effects of the MT2 receptor on glucose uptake and transport in trophoblasts. The results showed that the genotype and allele frequencies of rs10830963 were significantly different between GDM and normal pregnant women. Additionally, melatonin could stimulate glucose uptake, GLUT4 and PPAR gamma protein expression in trophoblasts, which could be attenuated by MT2 receptor knockdown.

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2023)

Add to Collection

Review Cell Biology

Agomelatine: a potential novel approach for the treatment of memory disorder in neurodegenerative disease

Qiang Su et al.

Summary: Agomelatine is a medication used to treat major depressive episodes in adults by acting as a selective agonist of melatonin receptor 1A/melatonin receptor 1B and antagonist of 5-hydroxytryptamine 2C receptors. It reconstructs sleep-wake rhythms and normalizes circadian disturbances, as well as enhances the release of dopamine and noradrenaline, reducing depression and anxiety disorder. The combination of these effects makes agomelatine unique in the treatment of depression, anxiety, and circadian rhythm disorders.

NEURAL REGENERATION RESEARCH (2023)

Add to Collection

Article Clinical Neurology

Melatonin Treatment of Circadian Rhythm Sleep-Wake Disorder in Obese Children Affects the Brain-Derived Neurotrophic Factor Level

Xuesong Huang et al.

Summary: This study investigated the role of brain-derived neurotrophic factor (BDNF) in sleep regulation and its response to melatonin treatment in obese children with circadian rhythm sleep-wake disorder (CRSWD). The results showed that melatonin treatment effectively improved CRSWD and increased serum BDNF levels among obese children.

NEUROPEDIATRICS (2023)

Add to Collection

Review Cell Biology

Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders

Sheikh Bilal Ahmad et al.

Summary: Melatonin is a widely distributed molecule in nature and is produced by various organisms. It acts through melatonin receptors to regulate sleep and circadian rhythms. Melatonin also has antioxidant and anti-inflammatory properties, playing important roles in diseases such as cancer and neurodegenerative disorders.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2023)

Add to Collection

Review Biochemistry & Molecular Biology

Neuroprotective Effect of Melatonin on Sleep Disorders Associated with Parkinson's Disease

Xinyu Hu et al.

Summary: Parkinson's disease (PD) is a complex disorder with non-motor symptoms, including sleep disorders. Melatonin, with its regulatory effects, is expected to be a potential treatment for sleep disorders in PD. Ongoing clinical trials highlight its therapeutic effects in PD.

ANTIOXIDANTS (2023)

Add to Collection

Review Biochemistry & Molecular Biology

Oxidative Stress and Aging as Risk Factors for Alzheimer's Disease and Parkinson's Disease: The Role of the Antioxidant Melatonin

Jana Tchekalarova et al.

Summary: Aging and neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are linked by common features like mitochondrial dysfunction and protein aggregation. The rising costs of caring for elderly patients with these diseases is a major issue in today's demographic crisis. Oxidative stress and imbalanced antioxidant defense system play crucial roles in age-related neurodegeneration, and diminished melatonin release with aging further increases susceptibility to these diseases. Understanding the underlying mechanisms and melatonin's role is important for developing precise treatment strategies.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection

Article Biochemistry & Molecular Biology

Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis

Majid Ghareghani et al.

Summary: The study found that melatonin functions through its receptors in the brain of multiple sclerosis (MS) patients. Excessive intake of melatonin exacerbates inflammation and immune cell migration to lesion areas. Therefore, monitoring the intake of melatonin in patients is necessary during treatment.

EXPERIMENTAL AND MOLECULAR MEDICINE (2023)

Add to Collection

Review Neurosciences

Analgesic efficacy of sleep-promoting pharmacotherapy in patients with chronic pain: a systematic review and meta-analysis

Emelie Andersson et al.

Summary: Dysregulation of sleep is linked to heightened pain sensitivity and may contribute to chronic pain. Sleep-promoting pharmacotherapy shows potential in improving pain control.

PAIN REPORTS (2023)

Add to Collection

Review Biochemistry & Molecular Biology

Melatonin: A smart molecule in the DNA repair system

Seyed Mostafa Mir et al.

Summary: DNA repair is crucial for protecting DNA molecules from damage caused by various factors, and melatonin plays a role in this repair process by acting as an antioxidant. The mechanisms of DNA repair, such as homologous recombination repair and non-homologous end-joining, are important for maintaining DNA integrity.

CELL BIOCHEMISTRY AND FUNCTION (2022)

Add to Collection

Review Neurosciences

Melatonin: A Potential Shield against Electromagnetic Waves

Maya Jammoul et al.

Summary: This review explores the relationship between melatonin, electromagnetic fields (EMF), and oxidative stress, and proposes a protective mechanism of melatonin against EMF-induced oxidative stress. The study suggests that melatonin acts as a free radical scavenger and highlights the potential therapeutic benefits of melatonin for electromagnetic hypersensitivity (EHS).

CURRENT NEUROPHARMACOLOGY (2022)

Add to Collection

Review Pharmacology & Pharmacy

Melatonin as a complementary and prophylactic agent against COVID-19 in high-risk populations: A narrative review of recent findings from clinical and preclinical studies

Abdolkarim Hosseini et al.

Summary: The psychological stress caused by COVID-19 has had negative impacts on individuals and professions, while melatonin may serve as a potential medication to alleviate stress and improve sleep.

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2022)

Add to Collection

Review Peripheral Vascular Disease

Controlled-release oral melatonin supplementation for hypertension and nocturnal hypertension: A systematic review and meta-analysis

Eric Kam-Pui Lee et al.

Summary: Oral melatonin may be a potential alternative treatment for hypertension and nocturnal hypertension, but high-quality meta-analyses are lacking. The meta-analysis suggests that controlled-release melatonin can reduce asleep systolic blood pressure and improve sleep quality and total sleep time.

JOURNAL OF CLINICAL HYPERTENSION (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy

Niloufar Targhazeh et al.

Summary: Melatonin, the major secretory product of the pineal gland, has not only regulatory effects on sleep, mood, and circadian rhythms but also shows promising potential as an agent in cancer treatment. It can inhibit cancer cell invasion and metastasis, reduce cell proliferation, enhance anti-cancer immunity, and modulate apoptosis and the cell cycle.

BIOCHIMIE (2022)

Add to Collection

Article Environmental Sciences

Chronic-Exposure Low-Frequency Magnetic Fields (Magnetotherapy and Magnetic Stimulation) Influence Serum Serotonin Concentrations in Patients with Low Back Pain-Clinical Observation Study

Marta Woldanska-Okonska et al.

Summary: This study found that low-frequency magnetic fields can increase the concentration of serotonin, which may be used in the treatment of diseases with low serotonin concentrations. Magnetotherapy and magnetic stimulation have similar effects.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Add to Collection

Article Neurosciences

Clock Genes Profiles as Diagnostic Tool in (Childhood) ADHD-A Pilot Study

Alexander Dueck et al.

Summary: This study compared circadian rhythms at the behavioral, endocrine, and molecular levels between children with ADHD and age- and BMI-matched controls. Significant differences were found in sleep onset and duration, cortisol secretion profiles, and expression of clock genes in the ADHD group. The analysis of circadian molecular rhythms may provide a new approach for diagnosing ADHD in children and adults.

BRAIN SCIENCES (2022)

Add to Collection

Editorial Material Endocrinology & Metabolism

Melatonin controversies, an update

Jean A. Boutin et al.

Summary: The article highlights the controversies and limitations in the field of melatonin research, calling for discussion and proposing guidelines to advance the field.

JOURNAL OF PINEAL RESEARCH (2021)

Add to Collection

Article Endocrinology & Metabolism

Weekly, seasonal, and chronotype-dependent variation of dim-light melatonin onset

Giulia Zerbini et al.

Summary: The study reveals that both season and weekly schedule impact the phase of entrainment and sleep in humans. In summer, the phase of entrainment is about 1 hour earlier compared to winter, with shorter sleep duration, particularly affecting individuals with later chronotypes. These findings suggest that the phase of entrainment is linked to midday or midnight rather than sunrise or sunset.

JOURNAL OF PINEAL RESEARCH (2021)

Add to Collection

Article Clinical Neurology

Workshop report. Circadian rhythm sleep-wake disorders: gaps and opportunities

Jeanne F. Duffy et al.

Summary: This White Paper presents the results of a workshop co-sponsored by the Sleep Research Society (SRS) and the Society for Research on Biological Rhythms (SRBR) to identify gaps in diagnosis and treatment, and areas of high-priority research in circadian rhythm sleep-wake disorders. CRSWD are caused by alterations in the circadian time-keeping system and may affect a large number of individuals in the United States.

SLEEP (2021)

Add to Collection

Review Biotechnology & Applied Microbiology

Role and Therapeutic Potential of Melatonin in Various Type of Cancers

Sangiliyandi Gurunathan et al.

Summary: Cancer is the second leading cause of death worldwide, and melatonin has been shown to have oncostatic and anticancer properties by directly affecting carcinogenesis and indirectly disrupting the circadian cycle.

ONCOTARGETS AND THERAPY (2021)

Add to Collection

Article Clinical Neurology

Circadian Rhythm Disorders and Corresponding Functional Brain Abnormalities in Young Female Nurses: A Preliminary Study

Xiaoli Wu et al.

Summary: This study investigated the relationship between circadian rhythm disorders caused by night shift work and changes in brain functional connectivity. The results showed that night shift nurses had lower sleep quality and melatonin levels, as well as alterations in brain FC and ReHo. The findings suggest that night shift work can lead to both physiological and functional brain changes.

FRONTIERS IN NEUROLOGY (2021)

Add to Collection

Editorial Material Endocrinology & Metabolism

Journal of Pineal Research guideline for authors: Measuring melatonin in humans

Steven W. Lockley

JOURNAL OF PINEAL RESEARCH (2020)

Add to Collection

Article Biology

Melatonin Levels and Low-Frequency Magnetic Fields in Humans and Rats: New Insights From a Bayesian Logistic Regression

Nicolas F. Bouche et al.

BIOELECTROMAGNETICS (2019)

Add to Collection

Article Neurosciences

Research Paper: Effects of the Extremely Low Frequency Electromagnetic Fields on NMDA-Receptor Gene Expression and Visual Working Memory in Male Rhesus Macaques

Masoomeh Kazemi et al.

BASIC AND CLINICAL NEUROSCIENCE (2018)

Add to Collection

Review Biochemistry & Molecular Biology

Effects of Melatonin and Its Analogues on Pancreatic Inflammation, Enzyme Secretion, and Tumorigenesis

Jolanta Jaworek et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Add to Collection

Review Environmental Sciences

Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption

Ruth M. Lunn et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2017)

Add to Collection

Review Cell Biology

Extremely low frequency electromagnetic fields stimulation modulates autoimmunity and immune responses: a possible immuno-modulatory therapeutic effect in neurodegenerative diseases

Fabio Guerriero et al.

NEURAL REGENERATION RESEARCH (2016)

Add to Collection

Article Endocrinology & Metabolism

Membrane receptor-dependent Notch1/Hes1 activation by melatonin protects against myocardial ischemia-reperfusion injury: invivo and invitro studies

Liming Yu et al.

JOURNAL OF PINEAL RESEARCH (2015)

Add to Collection

Review Biotechnology & Applied Microbiology

Influence of Electric, Magnetic, and Electromagnetic Fields on the Circadian System: Current Stage of Knowledge

Bogdan Lewczuk et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Add to Collection

Review Endocrinology & Metabolism

Can disturbances in the atmospheric electric field created by powerline corona ions disrupt melatonin production in the pineal gland?

Denis L. Henshaw et al.

JOURNAL OF PINEAL RESEARCH (2008)

Add to Collection

Article Biology

Occupational magnetic field exposure and melatonin: Interaction with light-at-night

Jukka Juutilainen et al.

BIOELECTROMAGNETICS (2006)

Add to Collection

Article Multidisciplinary Sciences

The circadian basis of winter depression

Alfred J. Lewy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Add to Collection

Article Endocrinology & Metabolism

Chronic exposure to 25-80-mu T, 200-Hz magnetic field does not influence serum melatonin concentrations in patients with low back pain

M Karasek et al.

JOURNAL OF PINEAL RESEARCH (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.