Microfluidics and Organoids, the Power Couple of Developmental Biology and Oncology Studies

Organoids are an advanced cell model that hold the key to unlocking a deeper understanding of in vivo cellular processes. This model can be used in understanding organ development, disease progression, and treatment efficacy. As the scientific world embraces the model, it must also establish the best practices for cultivating organoids and utilizing them to the greatest potential in assays. Microfluidic devices are emerging as a solution to overcome the challenges of organoids and adapt assays. Unfortunately, the various applications of organoids often depend on specific features in a device. In this review, we discuss the options and considerations for features and materials depending on the application and development of the organoid.

Automated summary

Organoids are a valuable cell model used to study organ development, disease progression, and treatment effectiveness. The use of microfluidic devices is emerging as a solution to overcome challenges and optimize organoid assays. However, the specific features and materials of these devices must be carefully considered based on the intended application and organoid development.