☆ 4.7 Review

EP300 as a Molecular Integrator of Fibrotic Transcriptional Programs

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

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The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis

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ANNALS OF THE RHEUMATIC DISEASES (2014)

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Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

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p300 Is Elevated in Systemic Sclerosis and Its Expression Is Positively Regulated by TGF-β: Epigenetic Feed-Forward Amplification of Fibrosis

Asish K. Ghosh et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)

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Article Oncology

Small-Molecule Inhibitors of Acetyltransferase p300 Identified by High-Throughput Screening Are Potent Anticancer Agents

Heng Yang et al.

MOLECULAR CANCER THERAPEUTICS (2013)

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Article Biochemistry & Molecular Biology

Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation

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NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)

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Review Biochemistry & Molecular Biology

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

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NATURE MEDICINE (2012)

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Editorial Material Biochemistry & Molecular Biology

Scraping fibrosis

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NATURE MEDICINE (2011)

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Virtual Ligand Screening of the p300/CBP Histone Acetyltransferase: Identification of a Selective Small Molecule Inhibitor

Erin M. Bowers et al.

CHEMISTRY & BIOLOGY (2010)

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Article Cardiac & Cardiovascular Systems

Prediction of All-Cause Mortality From Global Longitudinal Speckle Strain Comparison With Ejection Fraction and Wall Motion Scoring

Tony Stanton et al.

CIRCULATION-CARDIOVASCULAR IMAGING (2009)

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Article Biochemistry & Molecular Biology

Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator

Asish K. Ghosh et al.

FASEB JOURNAL (2009)

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Article Biochemistry & Molecular Biology

Inhibition of Lysine Acetyltransferase KAT3B/p300 Activity by a Naturally Occurring Hydroxynaphthoquinone, Plumbagin

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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

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CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53

Dingding Shi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

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Article Biochemistry & Molecular Biology

Regulation of the p300 HAT domain via a novel activation loop

PR Thompson et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)

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Article Biochemistry & Molecular Biology

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

K Balasubramanyam et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

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Article Multidisciplinary Sciences

Polyubiquitination of p53 by a ubiquitin ligase activity of p300

SR Grossman et al.

SCIENCE (2003)

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