4.7 Article

Viscum album Induces Apoptosis by Regulating STAT3 Signaling Pathway in Breast Cancer Cells

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

Nano-biomarker-Based Surface-Enhanced Raman Spectroscopy for Selective Diagnosis of Gallbladder and Liver Injury

Sanghwa Lee et al.

Summary: A biosensing chip using surface-enhanced Raman spectroscopy has been developed to monitor the health status of patients after living donor liver transplantation. By analyzing nanometer biomarkers in the bile and histopathology, the chip can detect and differentiate between damaged gallbladder and liver damage caused by bile duct ligation.

BIOCHIP JOURNAL (2022)

Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

Review Oncology

STAT3 Signaling in Breast Cancer: Multicellular Actions and Therapeutic Potential

Sarah Q. To et al.

Summary: This review explores the role of the STAT3 signaling pathway in breast cancer and its correlation with disease progression and metastasis. The study discusses the function of this signaling cascade in the tumor microenvironment, as well as the contribution of IL-6 family cytokines to cancer and potential therapeutic targets.

CANCERS (2022)

Review Pharmacology & Pharmacy

Signal transducer and activator of transcription 3 signaling in tumor immune evasion

Luying Zhang et al.

Summary: The underlying mechanism of tumor immune evasion, particularly the role of STAT3 in promoting tumor cell escape from immune surveillance through regulating autophagy molecules, immune factors, and immunosuppressive cell recruitment, is discussed in this review. The article also highlights the significance of the research on STAT3 signaling and tumor immune evasion in the development of targeted drugs for immunotherapy.

PHARMACOLOGY & THERAPEUTICS (2022)

Article Biochemistry & Molecular Biology

Anti-Obesity Effect of Polygalin C Isolated from Polygala japonica Houtt. via Suppression of the Adipogenic and Lipogenic Factors in 3T3-L1 Adipocytes

Wona Jee et al.

Summary: The study showed that Polygalin C (PC) extracted from Polygala japonica Houtt. has a significant anti-obesity effect on 3T3-L1 adipocytes by reducing lipid accumulation, suppressing adipogenesis and lipogenesis factors, and regulating AMPK/ACC and MAPK/Akt signaling pathways.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Biotechnology & Applied Microbiology

Natural products in drug discovery: advances and opportunities

Atanas G. Atanasov et al.

Summary: Natural products and their analogues have historically played a significant role in pharmacotherapy, however, they also present challenges. Recent technological and scientific developments are addressing these challenges and revitalizing interest in natural products as drug leads, particularly for combating antimicrobial resistance.

NATURE REVIEWS DRUG DISCOVERY (2021)

Review Immunology

Necroptosis, pyroptosis and apoptosis: an intricate game of cell death

Damien Bertheloot et al.

Summary: Cell death is a fundamental physiological process in all living organisms, playing important roles in embryonic development, organ maintenance, aging, immune responses, and autoimmunity. Recent research has significantly increased our understanding of the mechanisms orchestrating different types of programmed cell death and how they affect the balance of cell fates. Various modalities of cell death, such as apoptosis, necroptosis, and pyroptosis, have been studied to highlight both common and unique pathways and their impact on the surrounding cells and the organism as a whole.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

Review Oncology

Targeting apoptosis in cancer therapy

Benedito A. Carneiro et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Review Chemistry, Medicinal

Biological activity of mistletoe: in vitro and in vivo studies and mechanisms of action

Anna Szurpnicka et al.

ARCHIVES OF PHARMACAL RESEARCH (2020)

Review Biochemistry & Molecular Biology

Cell Death in the Origin and Treatment of Cancer

Andreas Strasser et al.

MOLECULAR CELL (2020)

Review Biochemistry & Molecular Biology

Procaspase-3 Overexpression in Cancer: A Paradoxical Observation with Therapeutic Potential

Matthew W. Boudreau et al.

ACS CHEMICAL BIOLOGY (2019)

Article Integrative & Complementary Medicine

Effects of mistletoe products on pharmacokinetic drug turnover by inhibition and induction of cytochrome P450 activities

Michael Schink et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2017)

Article Oncology

Past, Present, and Future Challenges in Breast Cancer Treatment

George W. Sledge et al.

JOURNAL OF CLINICAL ONCOLOGY (2014)

Article Cell Biology

Caspase Functions in Cell Death and Disease

David R. McIlwain et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Review Plant Sciences

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

David J. Newman et al.

JOURNAL OF NATURAL PRODUCTS (2012)

Article Oncology

Genetic heterogeneity and cancer drug resistance

Nicholas C. Turner et al.

LANCET ONCOLOGY (2012)

Review Oncology

Apoptosis in cancer: from pathogenesis to treatment

Rebecca S. Y. Wong

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2011)

Review Oncology

Cell cycle, CDKs and cancer: a changing paradigm

Marcos Malumbres et al.

NATURE REVIEWS CANCER (2009)

Review Biochemistry & Molecular Biology

Mammalian cyclin-dependent kinases

M Malumbres et al.

TRENDS IN BIOCHEMICAL SCIENCES (2005)

Article Biochemistry & Molecular Biology

Evaluation of potential Stat3-regulated genes in human breast cancer

FC Hsieh et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)

Review Pharmacology & Pharmacy

Cell-cycle dysregulation and anticancer therapy

ZA Stewart et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2003)