4.1 Review

Obesity and Cancer: An Angiogenic and Inflammatory Link

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Regulation of Adipose Tissue Stem Cells Angiogenic Potential by Tumor Necrosis Factor-Alpha

Ekaterina S. Zubkova et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2016)

Article Pharmacology & Pharmacy

Metformin for Prevention and Treatment of Colon Cancer: A Reappraisal of Experimental and Clinical Data

Vladimir N. Anisimov

CURRENT DRUG TARGETS (2016)

Article Oncology

Insulin priming effect on estradiol-induced breast cancer metabolism and growth

Peninah M. Wairagu et al.

CANCER BIOLOGY & THERAPY (2015)

Review Biochemistry & Molecular Biology

Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer

Xuyi Wang et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)

Review Endocrinology & Metabolism

The role of the insulin/IGF system in cancer: lessons learned from clinical trials and the energy balance-cancer link

Laura W. Bowers et al.

FRONTIERS IN ENDOCRINOLOGY (2015)

Article Pathology

Hypercholesterolemia Induces Angiogenesis and Accelerates Growth of Breast Tumors in Vivo

Kristine Pelton et al.

AMERICAN JOURNAL OF PATHOLOGY (2014)

Article Endocrinology & Metabolism

Obesity and cancer pathogenesis

Nathan A. Berger

YEAR IN DIABETES AND OBESITY (2014)

Article Oncology

Metformin Inhibits Skin Tumor Promotion in Overweight and Obese Mice

L. Allyson Checkley et al.

CANCER PREVENTION RESEARCH (2014)

Article Oncology

Paradoxic effects of metformin on endothelial cells and angiogenesis

Katiuscia Dallaglio et al.

CARCINOGENESIS (2014)

Article Oncology

Anti-diabetic Drug Metformin: Challenges and Perspectives for Cancer Therapy

Kaniyampadi Sreenivasan Snima et al.

CURRENT CANCER DRUG TARGETS (2014)

Review Endocrinology & Metabolism

Antihyperglycaemic therapies and cancer risk

Stefan Z. Lutz et al.

DIABETES & VASCULAR DISEASE RESEARCH (2014)

Article Neurosciences

Chronic metformin treatment improves post-stroke angiogenesis and recovery after experimental stroke

Venugopal R. Venna et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2014)

Article Medicine, General & Internal

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

Cynthia L. Ogden et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)

Review Oncology

Obesity and pancreatic cancer

Giuseppe Preziosi et al.

SURGICAL ONCOLOGY-OXFORD (2014)

Review Physiology

Diabetes, pancreatic cancer, and metformin therapy

Jun Gong et al.

FRONTIERS IN PHYSIOLOGY (2014)

Article Gastroenterology & Hepatology

Association of Pancreatic Fatty Infiltration With Pancreatic Ductal Adenocarcinoma

Mika Hori et al.

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2014)

Article Oncology

Stromal disrupting effects of nab-paclitaxel in pancreatic cancer

R. Alvarez et al.

BRITISH JOURNAL OF CANCER (2013)

Review Oncology

The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer

Vladimir N. Anisimov et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2013)

Article Oncology

Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

Rakesh K. Jain

JOURNAL OF CLINICAL ONCOLOGY (2013)

Editorial Material Oncology

Can We Identify Predictive Biomarkers for Antiangiogenic Therapy of Cancer Using Mathematical Modeling?

Dan G. Duda et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)

Article Oncology

Hyperglycemia, Insulin Resistance, Impaired Pancreatic -Cell Function, and Risk of Pancreatic Cancer

Brian M. Wolpin et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)

Review Biochemistry & Molecular Biology

Metabolic roles of AMPK and metformin in cancer cells

Yeon Kyung Choi et al.

MOLECULES AND CELLS (2013)

Editorial Material Chemistry, Physical

Strategies for advancing cancer nanomedicine

Vikash P. Chauhan et al.

NATURE MATERIALS (2013)

Review Physiology

HYPOXIA AND ADIPOSE TISSUE FUNCTION AND DYSFUNCTION IN OBESITY

Paul Trayhurn

PHYSIOLOGICAL REVIEWS (2013)

Article Gastroenterology & Hepatology

Metformin Inhibits the Growth of Human Pancreatic Cancer Xenografts

Krisztina Kisfalvi et al.

PANCREAS (2013)

Review Pharmacology & Pharmacy

Adipocytes: Impact on tumor growth and potential sites for therapeutic intervention

Simona Hefetz-Sela et al.

PHARMACOLOGY & THERAPEUTICS (2013)

Article Multidisciplinary Sciences

CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer

Albrecht Neesse et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Cell & Tissue Engineering

Adipose-Derived Stem Cells Promote Angiogenesis and Tissue Formation for In Vivo Tissue Engineering

Ken Matsuda et al.

TISSUE ENGINEERING PART A (2013)

Article Multidisciplinary Sciences

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

Vikash P. Chauhan et al.

NATURE COMMUNICATIONS (2013)

Article Oncology

Leptin’s Pro-Angiogenic Signature in Breast Cancer

Ruben Gonzalez-Perez et al.

Cancers (2013)

Article Gastroenterology & Hepatology

IGF-1 and Its Receptor in Esophageal Cancer: Association with Adenocarcinoma and Visceral Obesity

Suzanne L. Doyle et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2012)

Article Oncology

Obesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issue

Stephen D. Hursting et al.

NUTRITION AND PHYSICAL ACTIVITY IN AGING, OBESITY, AND CANCER (2012)

Article Oncology

Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes

Rinat Yerushalmi et al.

BREAST CANCER RESEARCH AND TREATMENT (2012)

Article Oncology

Translational Therapeutic Opportunities in Ductal Adenocarcinoma of the Pancreas

Manuel Hidalgo et al.

CLINICAL CANCER RESEARCH (2012)

Article Endocrinology & Metabolism

Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model

Antonio Cittadini et al.

DIABETES (2012)

Article Biochemistry & Molecular Biology

Association between obesity and gallbladder cancer

Fei Wang et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2012)

Review Oncology

Insulin resistance: A significant risk factor of endometrial cancer

Nan Mu et al.

GYNECOLOGIC ONCOLOGY (2012)

Review Endocrinology & Metabolism

Metformin in cancer: translational challenges

Ryan J. O. Dowling et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2012)

Review Endocrinology & Metabolism

Minireview: The Year in Obesity and Cancer

Stephen D. Hursting

MOLECULAR ENDOCRINOLOGY (2012)

Article Multidisciplinary Sciences

Dichotomous effects of VEGF-A on adipose tissue dysfunction

Kai Sun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Cancer-associated adipocytes promotes breast tumor radioresistance

Ludivine Bochet et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Pharmacology & Pharmacy

Metformin restores endothelial function in aorta of diabetic rats

Cristina M. Sena et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Article Oncology

Dietary Energy Balance Modulates Prostate Cancer Progression in Hi-Myc Mice

Jorge Blando et al.

CANCER PREVENTION RESEARCH (2011)

Review Oncology

Beyond VEGF: Inhibition of the Fibroblast Growth Factor Pathway and Antiangiogenesis

Christopher Lieu et al.

CLINICAL CANCER RESEARCH (2011)

Review Urology & Nephrology

BMI and the risk of renal cell carcinoma

Barry B. McGuire et al.

CURRENT OPINION IN UROLOGY (2011)

Review Biotechnology & Applied Microbiology

Biology of Obesity: Lessons from Animal Models of Obesity

Keizo Kanasaki et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)

Review Multidisciplinary Sciences

Molecular mechanisms and clinical applications of angiogenesis

Peter Carmeliet et al.

NATURE (2011)

Review Biotechnology & Applied Microbiology

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

Peter Carmeliet et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Review Gastroenterology & Hepatology

The clinical significance of pancreatic steatosis

Mark M. Smits et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2011)

Review Multidisciplinary Sciences

Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia

Masabumi Shibuya

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2011)

Article Multidisciplinary Sciences

C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells

Sachie Hiratsuka et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Losartan inhibits collagen I synthesis and improves the distribution and efficacy of nanotherapeutics in tumors

Benjamin Diop-Frimpong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Chemistry, Applied

Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies

Vikash P. Chauhan et al.

ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 2 (2011)

Article Oncology

Obesity and Microvascular Invasion in Hepatocellular Carcinoma

Abby B. Siegel et al.

CANCER INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species

Akie Fujimoto et al.

FREE RADICAL RESEARCH (2010)

Editorial Material Oncology

Biomarkers of Antiangiogenic Therapy: How Do We Move From Candidate Biomarkers to Valid Biomarkers

Dan G. Duda et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

Article Gastroenterology & Hepatology

Antidiabetic Therapies Affect Risk of Pancreatic Cancer

Donghui Li et al.

GASTROENTEROLOGY (2009)

Article Medicine, General & Internal

Body Mass Index and Risk, Age of Onset, and Survival in Patients With Pancreatic Cancer

Donghui Li et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2009)

Article Biochemistry & Molecular Biology

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Nils Halberg et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Review Oncology

Biomarkers of response and resistance to antiangiogenic therapy

Rakesh K. Jain et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2009)

Article Biochemistry & Molecular Biology

Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human breast cancer cells

N. J. Sullivan et al.

ONCOGENE (2009)

Article Surgery

Obesity potentiates the growth and dissemination of pancreatic cancer

Nicholas J. Zyromski et al.

SURGERY (2009)

Article Public, Environmental & Occupational Health

Prediagnostic Adiponectin Concentrations and Pancreatic Cancer Risk in Male Smokers

Rachael Z. Stolzenberg-Solomon et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2008)

Article Hematology

VEGFR1 tyrosine kinase signaling promotes lymphangiogenesis as well as angiogenesis indirectly via macrophage recruitment

Masato Murakami et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)

Review Cardiac & Cardiovascular Systems

Angiogenesis and obesity

H. Roger Lijnen

CARDIOVASCULAR RESEARCH (2008)

Article Endocrinology & Metabolism

Adverse adipose phenotype and hyperinsulinemia in gravid mice deficient in placental growth factor

Bianca Hemmeryckx et al.

ENDOCRINOLOGY (2008)

Article Obstetrics & Gynecology

Leptin levels in serum depending on Body Mass Index in patients with endometrial hyperplasia and cancer

Aneta Cymbaluk et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2008)

Article Pharmacology & Pharmacy

Brain insulin, energy and glucose homeostasis; genes, environment and metabolic pathologies

Kyriaki Gerozissis

EUROPEAN JOURNAL OF PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice

I. Murano et al.

JOURNAL OF LIPID RESEARCH (2008)

Article Biochemistry & Molecular Biology

Genotype x diet interactions in mice predisposed to mammary cancer. I. Body weight and fat

Ryan R. Gordon et al.

MAMMALIAN GENOME (2008)

Article Oncology

Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones

Nomeli P. Nunez et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2008)

Article Endocrinology & Metabolism

Hypoxia and the endocrine and signalling role of white adipose tissue

Paul Trayhurn et al.

ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY (2008)

Review Oncology

FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

Christian Fischer et al.

NATURE REVIEWS CANCER (2008)

Article Oncology

Is obesity an independent prognosis factor in woman breast cancer?

Bilal Majed et al.

BREAST CANCER RESEARCH AND TREATMENT (2008)

Review Endocrinology & Metabolism

Adiposity, the metabolic syndrome, and breast cancer in African-American and white American women

David P. Rose et al.

ENDOCRINE REVIEWS (2007)

Article Endocrinology & Metabolism

Plasma adiponectin concentrations and risk of incident breast cancer

Shelley S. Tworoger et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)

Review Oncology

Significance of interleukin-6 (IL-6) in breast cancer (review)

Heike Knuepfer et al.

BREAST CANCER RESEARCH AND TREATMENT (2007)

Article Endocrinology & Metabolism

Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

Naomi Hosogai et al.

DIABETES (2007)

Review Peripheral Vascular Disease

Tumor microvasculature and microenvironment: Targets for anti-angiogenesis and normalization

Dai Fukumura et al.

MICROVASCULAR RESEARCH (2007)

Article Oncology

High-fat, high-sucrose, and high-cholesterol diets accelerate tumor growth and metastasis in tumor-bearing mice

Yoshiyuki Kimura et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2007)

Article Oncology

Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma

Wendy Cozen et al.

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2006)

Article Medicine, General & Internal

Adult weight change and risk of postmenopausal breast cancer

AH Eliassen et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)

Review Oncology

The role of nitric oxide in tumour progression

Dai Fukumura et al.

NATURE REVIEWS CANCER (2006)

Article Hematology

Metformin inhibits proinflammatory responses and nuclear factor-κB in human vascular wall cells

K Isoda et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)

Article Critical Care Medicine

Interleukin-8

DG Remick

CRITICAL CARE MEDICINE (2005)

Article Endocrinology & Metabolism

Modulation of angiogenesis during adipose tissue development in murine models of obesity

G Voros et al.

ENDOCRINOLOGY (2005)

Article Endocrinology & Metabolism

Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-α and IL-6

HS Park et al.

DIABETES RESEARCH AND CLINICAL PRACTICE (2005)

Article Medicine, General & Internal

Metformin and reduced risk of cancer in diabetic patients

JMM Evans et al.

BMJ-BRITISH MEDICAL JOURNAL (2005)

Article Immunology

Role of interleukin-6 in mortality from and physiologic response to sepsis

DG Remick et al.

INFECTION AND IMMUNITY (2005)

Article Medicine, General & Internal

A potential decline in life expectancy in the United States in the 21st century

SJ Olshansky et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Review Immunology

Leptin in immunology

G Matarese et al.

JOURNAL OF IMMUNOLOGY (2005)

Article Medicine, General & Internal

Actual causes of death in the United States, 2000

AH Mokdad et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2004)

Review Biochemistry & Molecular Biology

Obesity and cancer

EE Calle et al.

ONCOGENE (2004)

Article Gastroenterology & Hepatology

Obesity and hepatocellular carcinoma

SH Caldwell et al.

GASTROENTEROLOGY (2004)

Article Cardiac & Cardiovascular Systems

Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis

D Fukumura et al.

CIRCULATION RESEARCH (2003)

Review Endocrinology & Metabolism

Adiponectin: More than just another fat cell hormone?

M Chandran et al.

DIABETES CARE (2003)

Article Medicine, General & Internal

Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults

EE Calle et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

Article Medicine, General & Internal

Obesity in adulthood and its consequences for, life expectancy: A life-table analysis

A Peeters et al.

ANNALS OF INTERNAL MEDICINE (2003)

Article Medicine, Research & Experimental

Obesity is associated with macrophage accumulation in adipose tissue

SP Weisberg et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Article Medicine, Research & Experimental

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

HY Xu et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Article Endocrinology & Metabolism

No decrease in free IGF-I with increasing insulin in obesity-related insulin resistance

W Ricart et al.

OBESITY RESEARCH (2001)

Review Multidisciplinary Sciences

Angiogenesis in cancer and other diseases

P Carmeliet et al.

NATURE (2000)