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In reply to comment on 'Therapeutic drug monitoring-guided treatment versus standard dosing of voriconazole for invasive aspergillosis in haematological patients: A multicentre, prospective, cluster randomised, crossover clinical trial'

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2023)

Related references

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Article Infectious Diseases

Therapeutic drug monitoring-guided treatment versus standard dosing of voriconazole for invasive aspergillosis in haematological patients: a multicentre, prospective, cluster randomised, crossover clinical trial

Anette Veringa et al.

Summary: This study investigated whether TDM-guided voriconazole treatment is superior to standard treatment for invasive aspergillosis. The results showed no significant difference in treatment outcome and adverse reactions between the TDM and non-TDM groups, but a higher proportion of voriconazole concentrations within the acceptable range were found in the TDM group.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2023)

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Management of drug-drug interactions of targeted therapies for haematological malignancies and triazole antifungal drugs

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LANCET HAEMATOLOGY (2022)

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Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics

Camille Lenoir et al.

Summary: The study found that under inflammatory conditions, interleukin-6 can downregulate cytochrome P450 activity through pretranscriptional and posttranscriptional mechanisms. The impact of elevated IL-6 levels in combination with drug interactions with esomeprazole on CYP3A and CYP2C19 was accurately predicted using a physiologically based pharmacokinetic (PBPK) model.

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2022)

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Voriconazole metabolism is influenced by severe inflammation: a prospective study

Anette Veringa et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2017)

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Article Dermatology

Evolution of procalcitonin, C-reactive protein and fibrinogen levels in neutropenic leukaemia patients with invasive pulmonary aspergillosis or mucormycosis

Marjorie Roques et al.

MYCOSES (2016)

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Article Immunology

The Effect of Therapeutic Drug Monitoring on Safety and Efficacy of Voriconazole in Invasive Fungal Infections: A Randomized Controlled Trial

Wan Beom Park et al.

CLINICAL INFECTIOUS DISEASES (2012)

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