Application of new indicators to assess the quality of antimicrobial use in intensive care units

Review Infectious Diseases

Antimicrobial consumption in patients with COVID-19: a systematic review and meta-analysis

Sidra Khan et al.

Summary: Prescribing antimicrobials for COVID-19 patients has become common practice since the onset of the pandemic. A systematic literature search identified a high antimicrobial consumption rate in lower and middle-income countries compared to high-income countries. Implementing appropriate antimicrobial stewardship interventions is necessary to address the high consumption of antimicrobials in COVID-19 patients.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2022)

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Article Immunology

Empiric Antibacterial Therapy and Community-onset Bacterial Coinfection in Patients Hospitalized With Coronavirus Disease 2019 (COVID-19): A Multi-hospital Cohort Study

Valerie M. Vaughn et al.

Summary: Among 1705 hospitalized COVID-19 patients, 56.6% received early empiric antibacterial therapy, while only 3.5% had confirmed community-onset bacterial infections. The use of early empiric antibacterials varied widely across hospitals.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Infectious Diseases

Evolution of Antimicrobial Consumption During the First Wave of COVID-19 Pandemic

Santiago Grau et al.

Summary: The study found an increase in antimicrobial consumption during the first wave of COVID-19 pandemic, especially in the ICU. Different antibiotics showed a clear temporal pattern in their usage. Availability of updated protocols and antimicrobial stewardship programs are essential to optimize these outcomes.

ANTIBIOTICS-BASEL (2021)

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Article Infectious Diseases