☆ 4.7 Article

Electroacupuncture at ST36 acupoint regulates stem cells during experimental autoimmune encephalomyelitis

INTERNATIONAL IMMUNOPHARMACOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Biochemistry & Molecular Biology

Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study

Angela Genchi et al.

Summary: This study conducted a phase 1 clinical trial evaluating the feasibility, safety and tolerability of intrathecally transplanted human fetal neural precursor cells (hfNPCs) in patients with progressive multiple sclerosis (PMS). The results demonstrated that hfNPC therapy is feasible, safe and tolerable in PMS patients.

NATURE MEDICINE (2023)

Add to Collection

Article Clinical Neurology

Hematopoietic Stem Cell Transplantation in People With Active Secondary Progressive Multiple Sclerosis

Giacomo Boffa et al.

Summary: This study compared the effects of autologous hematopoietic stem cell transplantation (AHSCT) with other anti-inflammatory disease-modifying therapies (DMTs) on long-term disability worsening in active secondary progressive multiple sclerosis (SPMS). The results showed that AHSCT was associated with a slower disability progression and a higher likelihood of disability improvement compared to standard immunotherapy.

NEUROLOGY (2023)

Add to Collection

Review Neurosciences

The interplay between T helper cells and brain barriers in the pathogenesis of multiple sclerosis

Gabriele Angelini et al.

Summary: The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB) are two complex structures that protect the central nervous system (CNS) from harmful agents and immune cells. During neuroinflammatory disorders like multiple sclerosis (MS), the BBB and BCSFB undergo changes that allow immune cells to enter the CNS and contribute to the disease. T helper (Th) lymphocytes, specifically Th1 and Th17 cells, play a key role in the pathogenesis of MS and interact with CNS barriers, leading to barrier dysfunction. This review discusses the molecular basis of the interactions between Th cells and CNS barriers and explores the role of the dura mater and arachnoid layer in CNS inflammatory diseases.

FRONTIERS IN CELLULAR NEUROSCIENCE (2023)

Add to Collection

Review Neurosciences

Glia Connect Inflammation and Neurodegeneration in Multiple Sclerosis

Ye Sun et al.

Summary: Multiple sclerosis (MS) is a chronic inflammatory disease that causes demyelination and neurodegeneration. Research on glial cells has provided insight into the connection between inflammation and neurodegeneration in MS.

NEUROSCIENCE BULLETIN (2023)

Add to Collection

Review Cell Biology

Implications of Hypothalamic Neural Stem Cells on Aging and Obesity-Associated Cardiovascular Diseases

Bhuvana Plakkot et al.

Summary: The hypothalamus, a major regulatory center in the brain, is involved in the regulation of aging through hypothalamic neural stem cells (htNSCs). Neural stem cells are important for repairing and regenerating brain cells and rejuvenating the brain tissue microenvironment. Cellular senescence, a state of irreversible cell cycle arrest, is associated with neuroinflammation, which can be upregulated by obesity. Obesity has been shown to accelerate aging, highlighting the need to study the dysregulation of htNSCs in obesity and develop strategies to address obesity-induced comorbidities associated with brain aging. This review will summarize hypothalamic neurogenesis in obesity and explore the potential of NSC-based regenerative therapy for obesity-induced cardiovascular conditions.

CELLS (2023)

Add to Collection

Article Immunology

Electroacupuncture Pretreatment at Zusanli (ST36) Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice by Reducing Oxidative Stress via Activating Vagus Nerve-Dependent Nrf2 Pathway

Haochen Jiang et al.

Summary: This study investigated the effect of acupuncture on hepatic ischemia/reperfusion injury and found that acupuncture treatment at Zusanli point (ST36) can ameliorate hepatic injury by alleviating oxidative stress and inflammation through activating the Nrf2 signal pathway.

JOURNAL OF INFLAMMATION RESEARCH (2023)

Add to Collection

Article Biochemistry & Molecular Biology

Therapeutical growth in oligodendroglial fate induction via transdifferentiation of stem cells for neuroregenerative therapy

Shrey Dwivedi et al.

Summary: The extensive usage of stem cell therapy and research in the treatment of neurodegenerative diseases and demyelinating disorders has proven its merits. Especially in cell replacement therapy, stem cells are induced into different cell lineages, including adult and progenitor cells, to be transplanted or used in disease modeling studies. This review focuses on the protocols and combinations of molecules and factors used to derive bona fide oligodendrocytes from in vitro differentiation of embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells, with special emphasis on MSC-derived oligodendrocytes.

BIOCHIMIE (2023)

Add to Collection

Review Clinical Neurology

Acupuncture for multiple sclerosis: A literature review

Faezeh Khodaie et al.

Summary: The review suggests that acupuncture can help improve symptoms and reduce relapses in patients with multiple sclerosis. It has positive effects on regulating the neuro-immune system, improving quality of life, reducing fatigue, improving bladder function, reducing spasms and pain, etc.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2022)

Add to Collection

Review Cell Biology

Regulating Endogenous Neural Stem Cell Activation to Promote Spinal Cord Injury Repair

Emily A. B. Gilbert et al.

Summary: Spinal cord injury affects millions of people worldwide, and there is currently no cure. Utilizing endogenous neural stem cells (NSCs) to replace lost cells and promote structural repair is a promising approach. However, there are still many unanswered questions regarding the heterogeneity of NSCs, their interaction with the environment, and factors that enhance their response.

CELLS (2022)

Add to Collection

Review Neurosciences

Mesenchymal Stem Cell Application and Its Therapeutic Mechanisms in Intracerebral Hemorrhage

Guoqiang Yang et al.

Summary: Intracerebral hemorrhage (ICH), a subtype of stroke with high mortality and disability rates, has a major socioeconomic burden, affecting two million people worldwide. Mesenchymal stem cells (MSCs) have shown potential in ICH treatment due to their neuroprotective, anti-inflammatory, and angiogenesis properties. This research field is important for developing new therapeutic strategies.

FRONTIERS IN CELLULAR NEUROSCIENCE (2022)

Add to Collection

Review Cell & Tissue Engineering

Mesenchymal stem cells and their microenvironment

Jiaxi Liu et al.

Summary: This review discusses the characteristics of MSCs, their interaction with the microenvironment, and the importance of the microenvironment in maintaining cell function and disease progression.

STEM CELL RESEARCH & THERAPY (2022)

Add to Collection

Article Clinical Neurology

Long-term Clinical Outcomes of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

Giacomo Boffa et al.

Summary: The study analyzed the long-term outcomes of autologous hematopoietic stem cell transplantation in patients with multiple sclerosis, showing that it prevents disability worsening in most patients and induces durable improvement in disability in patients with relapsing-remitting MS. The BEAM+ ATG conditioning protocol was found to be associated with a more pronounced suppression of clinical relapses and MRI inflammatory activity.

NEUROLOGY (2021)

Add to Collection

Editorial Material Multidisciplinary Sciences

Electroacupuncture activates neurons to switch off inflammation

Luis Ulloa

Summary: Neurons expressing a specific molecular marker are activated by 'electroacupuncture' stimulation and mediate the treatment's anti-inflammatory effects in a mouse model of sepsis.

NATURE (2021)

Add to Collection

Article Multidisciplinary Sciences

A neuroanatomical basis for electroacupuncture to drive the vagal-adrenal axis

Shenbin Liu et al.

Summary: The study reveals that the specificity of sensory neurons is crucial for driving specific autonomic pathways and anti-inflammatory effects at specific acupoints.

NATURE (2021)

Add to Collection

Article Cell Biology

Brain injury instructs bone marrow cellular lineage destination to reduce neuroinflammation

Samuel X. Shi et al.

Summary: Acute brain injury can mobilize circulating leukocytes to aggravate neural injury. This study demonstrates that bone marrow hematopoietic stem cells (HSCs) may be skewed towards the myeloid lineage in patients with intracerebral hemorrhage, leading to increased production of Ly6C(low) monocytes that suppress neuroinflammation and brain injury. The brain injury-induced modulation of HSC lineage development highlights the potential therapeutic effects of targeting bone marrow in neuroimmune interactions to reduce brain inflammation.

SCIENCE TRANSLATIONAL MEDICINE (2021)

Add to Collection

Review Cell Biology

Effect of Small Molecule on ex vivo Expansion of Cord Blood Hematopoietic Stem Cells: A Concise Review

Soudeh Ghafouri-Fard et al.

Summary: Hematopoietic stem cells play a crucial role in both preserving the blood system and potentially differentiating into non-hematopoietic cells for the treatment of human disorders.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Add to Collection

Review Pharmacology & Pharmacy

Failed, Interrupted, or Inconclusive Trials on Neuroprotective and Neuroregenerative Treatment Strategies in Multiple Sclerosis: Update 2015-2020

Niklas Huntemann et al.

Summary: Numerous drugs have been approved for treating multiple sclerosis in recent years, mainly focusing on immunomodulatory or immunosuppressive strategies rather than remyelination and neuroprotection. Neuroregenerative agents have shown potential in pre-clinical research and clinical trials, providing valuable insights into MS pathophysiology. Learning from failed trials can aid in translating pre-clinical findings into clinical applications for improved treatments.

DRUGS (2021)

Add to Collection

Article Immunology

Involvement of microRNA-155 in the mechanism of electroacupuncture treatment effects on experimental autoimmune encephalomyelitis

Ping Zhao et al.

Summary: Electroacupuncture (EA) treatment can alleviate clinical symptoms of EAE, reduce spinal cord demyelination, regulate inflammatory cytokine levels, and modulate miR-155 and POMC expression.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Add to Collection

Review Neurosciences

Multiple Sclerosis and the Endogenous Opioid System

Zoe Dworsky-Fried et al.

Summary: Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation, neuronal degeneration, and demyelination in the central nervous system. Emerging evidence suggests that the endogenous opioid system may play a role in the pathogenesis and symptoms of MS, through its immunomodulatory and neuroregulatory functions. Further research is needed to explore the mechanisms by which dysregulation of the opioid system contributes to the development and progression of MS.

FRONTIERS IN NEUROSCIENCE (2021)

Add to Collection

Editorial Material Multidisciplinary Sciences

Neurons that switch off inflammation

Luis Ulloa

NATURE (2021)

Add to Collection

Article Integrative & Complementary Medicine

Acupuncture/Electroacupuncture as an Alternative in Current Opioid Crisis

Usman Ali et al.

CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2020)

Add to Collection

Review Clinical Neurology

Treatment and management of cognitive dysfunction in patients with multiple sclerosis

John DeLuca et al.

NATURE REVIEWS NEUROLOGY (2020)

Add to Collection

Review Medicine, General & Internal

Treatment of Multiple Sclerosis: A Review

Stephen L. Hauser et al.

AMERICAN JOURNAL OF MEDICINE (2020)

Add to Collection

Article Neurosciences

[Met5]-enkephalin preserves diffusion metrics in EAE mice

Chirag Patel et al.

BRAIN RESEARCH BULLETIN (2020)

Add to Collection

Article Neurosciences

Electro-Acupuncture Promotes the Differentiation of Endogenous Neural Stem Cells via Exosomal microRNA 146b After Ischemic Stroke

Shenghang Zhang et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2020)

Add to Collection

Article Clinical Neurology

Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Valery L. Feigin et al.

LANCET NEUROLOGY (2019)

Add to Collection

Review Clinical Neurology

Epidemiology and treatment of multiple sclerosis in elderly populations

Caila B. Vaughn et al.

NATURE REVIEWS NEUROLOGY (2019)

Add to Collection

Review Medicine, General & Internal

Multiple sclerosis

Alan J. Thompson et al.

LANCET (2018)

Add to Collection

Review Cell Biology

Acupuncture and neuroregeneration in ischemic stroke

Qwang-Yuen Chang et al.

NEURAL REGENERATION RESEARCH (2018)

Add to Collection

Review Neurosciences

Multiple Sclerosis: Mechanisms and Immunotherapy

Clare Baecher-Allan et al.

NEURON (2018)

Add to Collection

Article Medicine, Research & Experimental

Neural Regulation of Bone and Bone Marrow

Maria Maryanovich et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2018)

Add to Collection

Article Cell Biology

Electro-Acupuncture at Zusanli Acupoint (ST36) Suppresses Inflammation in Allergic Contact Dermatitis Via Triggering Local IL-10 Production and Inhibiting p38 MAPK Activation

Zhigang Wang et al.

INFLAMMATION (2017)

Add to Collection

Review Biochemistry & Molecular Biology

Mechanisms of Acupuncture Therapy in Ischemic Stroke Rehabilitation: A Literature Review of Basic Studies

Lina M. Chavez et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Add to Collection

Article Multidisciplinary Sciences

Hypothalamic regulation of regionally distinct adult neural stem cells and neurogenesis

Alex Paul et al.

SCIENCE (2017)

Add to Collection

Review Biochemistry & Molecular Biology

Nerve Stimulation: Immunomodulation and Control of Inflammation

Luis Ulloa et al.

TRENDS IN MOLECULAR MEDICINE (2017)

Add to Collection

Review Cell Biology

Haematopoietic stem cells: past, present and future

Ashley P. Ng et al.

CELL DEATH DISCOVERY (2017)

Add to Collection

Review Clinical Neurology

Cell-based therapeutic strategies for multiple sclerosis

Neil J. Scolding et al.

BRAIN (2017)

Add to Collection

Article Cell Biology

Electro-Acupuncture Promotes Endogenous Multipotential Mesenchymal Stem Cell Mobilization into the Peripheral Blood

Lizhen Liu et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)

Add to Collection

Article Integrative & Complementary Medicine

Acupuncture Induces the Proliferation and Differentiation of Endogenous Neural Stem Cells in Rats with Traumatic Brain Injury

Shuting Jiang et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2016)

Add to Collection

Article Clinical Neurology

Epidemiology of Multiple Sclerosis

Jonathan Howard et al.

NEUROLOGIC CLINICS (2016)

Add to Collection

Article Medicine, General & Internal

Cell therapy for multiple sclerosis: an evolving concept with implications for other neurodegenerative diseases

Claire M. Rice et al.

LANCET (2013)

Add to Collection

Article Multidisciplinary Sciences

The Mechanism of Effective Electroacupuncture on T Cell Response in Rats with Experimental Autoimmune Encephalomyelitis

Yumei Liu et al.

PLOS ONE (2013)

Add to Collection

Review Cell Biology

Adult stem cells and multiple sclerosis

N. Scolding

CELL PROLIFERATION (2011)

Add to Collection

Article Immunology

The effect of electroacupuncture on T cell responses in rats with experimental autoimmune encephalitis

Yu-mei Liu et al.

JOURNAL OF NEUROIMMUNOLOGY (2010)

Add to Collection

Review Biochemistry & Molecular Biology

Mechanisms and functional implications of adult neurogenesis

Chunmei Zhao et al.

CELL (2008)

Add to Collection

Review Medicine, General & Internal

Multiple sclerosis

Alastair Compston et al.

LANCET (2008)

Add to Collection

© Peeref 2019-2024. All rights reserved.