4.7 Article

Mesenchymal Stem Cells and Myeloid-Derived Suppressor Cells Interplay in Adjuvant-Induced Arthritis Rat Model

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Some important inhibitors and mechanisms of rheumatoid arthritis

Shiyang Zhou et al.

Summary: Rheumatoid arthritis is a chronic disease that seriously affects human health and quality of life. It is currently incurable and can only be controlled and treated with medication.

CHEMICAL BIOLOGY & DRUG DESIGN (2022)

Article Chemistry, Analytical

Peptide-based electrochemical sensor with nanogold enhancement for detecting rheumatoid arthritis

Ching-Yu Lin et al.

Summary: The study developed a peptide-based electrochemical sensor for detecting autoantibodies in rheumatoid arthritis. The new method showed better sensitivity and accuracy compared to the traditional anti-CCP ELISA method.

TALANTA (2022)

Article Biology

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-kappa B signaling pathway

Gaoran Ge et al.

Summary: The study revealed that punicalagin could ameliorate pathological inflammation in rheumatoid arthritis by modulating macrophage polarization and inhibiting pyroptosis, suggesting its great potential as a therapeutic treatment for human RA.

SCIENCE CHINA-LIFE SCIENCES (2022)

Review Cell & Tissue Engineering

Mesenchymal stem cells and natural killer cells interaction mechanisms and potential clinical applications

Batol Abbasi et al.

Summary: This article discusses the interaction and signaling pathway between NK cells and MSCs, as well as their importance in clinical applications.

STEM CELL RESEARCH & THERAPY (2022)

Article Nanoscience & Nanotechnology

Topical Nano-Vesicular Spanlastics of Celecoxib: Enhanced Anti-Inflammatory Effect and Down-Regulation of TNF-α, NF-κB and COX-2 in Complete Freund's Adjuvant-Induced Arthritis Model in Rats

Eman Alaaeldin et al.

Summary: The study aimed to develop a site-specific delivery system for Celecoxib using spanlastic nanovesicles or niosomes, to improve therapeutic outcomes while avoiding systemic administration of large doses. The developed spanlastic nano-vesicle formulation showed higher transdermal flux and permeability coefficient compared to other investigated formulations, effectively reducing inflammation markers in a rat model of arthritis.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

Review Medicine, Research & Experimental

The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update

Jamshid Gholizadeh Navashenaq et al.

Summary: Rheumatoid arthritis (RA) is an autoimmune disease affecting joints, with unclear etiology but involving immune mechanisms. Immune cells migrate to the joints during disease onset, and the shift to Th1 and Th17 immune responses is crucial in RA development. Myeloid-derived suppressor cells (MDSCs) regulate immune system, their specific functions in RA need further investigation.

LIFE SCIENCES (2021)

Review Pharmacology & Pharmacy

Emerging Roles of Myeloid-Derived Suppressor Cells in Diabetes

Shiqi Wang et al.

Summary: Research has shown that MDSC plays an important immunosuppressive role in the diabetic microenvironment. Understanding the manifestations and subsets of MDSC is crucial for studying the pathogenesis and treatment of diabetes.

FRONTIERS IN PHARMACOLOGY (2021)

Article Cell Biology

Bone marrow cells are differentiated into MDSCs by BCC-Ex through down-regulating the expression of CXCR4 and activating STAT3 signalling pathway

Quan-Wen Liu et al.

Summary: Research has shown that breast cancer cell-secreted exosomes can induce differentiation of bone marrow cells into MDSCs and inhibit the proliferation of T lymphocytes, creating an immunosuppressive microenvironment for cancer cells.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Review Medicine, General & Internal

Myeloid-Derived Suppressor Cells and Mesenchymal Stem/Stromal Cells in Myeloid Malignancies

Suncica Kapor et al.

Summary: This review discusses the main features of MDSCs and MSCs in myeloid malignancies, revealing that MDSCs are elevated in numbers and exhibit strong immunosuppressive capabilities, while MSCs not only have immunosuppressive properties but also regulate the growth, apoptosis, and chemotherapy resistance of myeloid leukemia cells.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Immunology

IL-6 in inflammation, autoimmunity and cancer

Toshio Hirano

Summary: IL-6 is involved in various physiological processes including immune responses and inflammation. It plays a crucial role in chronic inflammation and cytokine storms, such as seen in COVID-19. The IL-6 amplifier, involving NF-kappa B and STAT3, is a key mechanism in promoting uncontrolled inflammatory responses.

INTERNATIONAL IMMUNOLOGY (2021)

Article Cell & Tissue Engineering

Immunomodulatory effect of human bone marrow-derived mesenchymal stromal/stem cells on peripheral blood T cells from rheumatoid arthritis patients

Monia Pedrosa et al.

JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2020)

Article Cell Biology

Adipose-resident myeloid-derived suppressor cells modulate immune cell homeostasis in healthy mice

Katlin B. Stivers et al.

IMMUNOLOGY AND CELL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Understanding the Differentiation, Expansion, Recruitment and Suppressive Activities of Myeloid-Derived Suppressor Cells in Cancers

Hui Xuan Lim et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Cell & Tissue Engineering

Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis

Jingjing Qi et al.

STEM CELL RESEARCH & THERAPY (2020)

Article Medicine, General & Internal

N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis

Hae-Rim Kim et al.

KOREAN JOURNAL OF INTERNAL MEDICINE (2019)

Review Rheumatology

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis

Zhu Chen et al.

NATURE REVIEWS RHEUMATOLOGY (2019)

Review Cell & Tissue Engineering

Mesenchymal stem cell perspective: cell biology to clinical progress

Mark F. Pittenger et al.

NPJ REGENERATIVE MEDICINE (2019)

Article Cell Biology

Separate roles of IL-6 and oncostatin M in mouse macrophage polarization in vitro and in vivo

Anisha Dubey et al.

IMMUNOLOGY AND CELL BIOLOGY (2018)

Review Oncology

Managing CNS disease in adults with acute lymphoblastic leukemia

Richard A. Larson

LEUKEMIA & LYMPHOMA (2018)

Article Immunology

Bone marrow mesenchymal stem cells suppress IL-9 in adjuvant-induced arthritis

Sahar Sobhy Abd Elhalem et al.

AUTOIMMUNITY (2018)

Article Immunology

Experimental animal models for rheumatoid arthritis

Narayan Choudhary et al.

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2018)

Article Biochemistry & Molecular Biology

Characterization of Multiple Cytokine Combinations and TGF-beta on Differentiation and Functions of Myeloid-Derived Suppressor Cells

Cho-Rong Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Biochemistry & Molecular Biology

Myeloid-derived suppressor cells exacerbate Sjogren's syndrome by inhibiting Th2 immune responses

Jingjing Qi et al.

MOLECULAR IMMUNOLOGY (2018)

Article Biotechnology & Applied Microbiology

The Expansion of Myeloid-Derived Suppressor Cells Is Associated with Joint Inflammation in Rheumatic Patients with Arthritis

Junqing Zhu et al.

BIOMED RESEARCH INTERNATIONAL (2018)

Article Immunology

CSF-1 in Inflammatory and Arthritic Pain Development

Reem Saleh et al.

JOURNAL OF IMMUNOLOGY (2018)

Article Medicine, Research & Experimental

Anti-inflammatory and antioxidant effects of mesenchymal and hematopoietic stem cells in a rheumatoid arthritis rat model

Hanan Abdelmawgoud et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2018)

Review Biochemistry & Molecular Biology

Interactions between mesenchymal stem cells and the immune system

Na Li et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

Article Cell & Tissue Engineering

Distinct Immunoregulatory Mechanisms in Mesenchymal Stem Cells: Role of the Cytokine Environment

Vladimir Holan et al.

STEM CELL REVIEWS AND REPORTS (2016)

Article Cell & Tissue Engineering

Distinct Immunoregulatory Mechanisms in Mesenchymal Stem Cells: Role of the Cytokine Environment

Vladimir Holan et al.

STEM CELL REVIEWS AND REPORTS (2016)

Article Rheumatology

Myeloid-derived suppressor cells have a proinflammatory role in the pathogenesis of autoimmune arthritis

Chunqing Guo et al.

ANNALS OF THE RHEUMATIC DISEASES (2016)

Review Hematology

Mesenchymal stromal cells in myeloid malignancies

Thomas Schroeder et al.

BLOOD RESEARCH (2016)

Review Cell Biology

Transcriptional regulation of myeloid-derived suppressor cells

Thomas Condamine et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2015)

Article Agriculture, Dairy & Animal Science

Enhanced adipogenic differentiation of bovine bone marrow-derived mesenchymal stem cells

So Hyun Lee et al.

JOURNAL OF APPLIED ANIMAL RESEARCH (2015)

Review Gastroenterology & Hepatology

Myeloid-Derived Suppressor Cells in Inflammatory Bowel Disease

Yeon-Jeong Kim et al.

INTESTINAL RESEARCH (2015)

Article Multidisciplinary Sciences

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

Simon Mendez-Ferrer et al.

NATURE (2010)

Meeting Abstract Hematology

Mesenchymal stem cells induce division arrest anergy of activated T cells

SJ Glennie et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)

Review Rheumatology

Upcoming biologic agents for the treatment of rheumatic diseases

JC Shanahan et al.

CURRENT OPINION IN RHEUMATOLOGY (2003)