4.7 Article

Lipid mediators derived from DHA alleviate DNCB-induced atopic dermatitis and improve the gut microbiome in BALB/c mice

Related references

Note: Only part of the references are listed.
Article Nutrition & Dietetics

Effects of Fish Oil, Lipid Mediators, Derived from Docosahexaenoic Acid, and Their Co-Treatment against Lipid Metabolism Dysfunction and Inflammation in HFD Mice and HepG2 Cells

Yan Su et al.

Summary: This study found that fish oil and lipid mediators derived from polyunsaturated fatty acids can prevent obesity and improve lipid metabolism. The combination of fish oil with lipid mediators showed a stronger therapeutic effect on nonalcoholic fatty liver disease and obesity, suggesting that it is a beneficial dietary strategy.

NUTRIENTS (2023)

Article Chemistry, Multidisciplinary

Picrasma quassioides (D.DON) Benn. Ethanolic Extract Improves Atopic Dermatitis and Hyperactivity Disorder in DNCB-Treated BALB/c Mice

Min-Jin Choi et al.

Summary: Gomokpi, a traditional medicinal herb, has been found to alleviate atopic dermatitis-like symptoms and behavioral abnormalities in mice. This effect may be attributed to its ability to inhibit TNF-alpha production and suppress the expression of inflammatory mediators in various cells. These findings suggest that Gomokpi could be a potential therapeutic option for atopic dermatitis.

APPLIED SCIENCES-BASEL (2022)

Article Food Science & Technology

Tea saponin extracted from seed pomace of Camellia oleifera Abel ameliorates DNCB-induced atopic dermatitis-like symptoms in BALB/c mice

Xueli Zhang et al.

Summary: This study evaluated the therapeutic effects of tea saponin from seed pomace of C. oleifera on atopic dermatitis. The results showed that tea saponin possesses antipruritic and anti-inflammatory properties, significantly reducing dermatitis and scratching in mice. It also normalized the skin barriers and inhibited the generation of inflammatory cytokines.

JOURNAL OF FUNCTIONAL FOODS (2022)

Article Integrative & Complementary Medicine

Inhibitory effect of Isatis tinctoria L. water extract on DNCB-induced atopic dermatitis in BALB/c mice and HaCaT cells

Ga-Yul Min et al.

Summary: The study demonstrates that PLG is a potent therapeutic agent for attenuating symptoms of atopic dermatitis by inhibiting inflammatory chemokine production and blocking the nuclear translocation of NF-kappa B p65.

CHINESE MEDICINE (2022)

Article Medicine, Research & Experimental

Paeonia lactiflora Pallas extract alleviates antibiotics and DNCB-induced atopic dermatitis symptoms by suppressing inflammation and changing the gut microbiota composition in mice

Seo Yeon Lee et al.

Summary: The Paeonia lactiflora Pallas extract (PL) has been found to alleviate symptoms of atopic dermatitis (AD) by regulating the gut microbiota. It suppresses inflammatory cytokines, induces Foxp3 expression, improves intestinal barrier integrity, and changes the gut microbiota composition.

BIOMEDICINE & PHARMACOTHERAPY (2022)

Article Integrative & Complementary Medicine

Salvianolic Acid A Suppresses DNCB-Induced Atopic Dermatitis-Like Symptoms in BALB/c Mice

Wi-Jin Jeon et al.

Summary: Salvianolic acid A has therapeutic potential for treating AD-like symptoms by suppressing skin hypertrophy and mast cell infiltration, reducing serum IgE levels, and lowering various cytokine levels. It may be effective in the treatment of AD.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2021)

Article Plant Sciences

Effects of chloroform fraction of Fritillariae Thunbergii Bulbus on atopic symptoms in a DNCB-induced atopic dermatitis-like skin lesion model and in vitro models

Eun-Young Kim et al.

Summary: Fritillariae thunbergii Bulbus (FT) exhibits anti-inflammatory effects, particularly in treating atopic dermatitis. The chloroform fraction extract of FT shows a better inhibitory effect on skin lesions and skin cells compared to the ethanol extract. Further research should focus on identifying the specific component in FT-Cl responsible for its anti-inflammatory properties.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Biochemistry & Molecular Biology

Mentha arvensis Essential Oil Exerts Anti-Inflammatory in LPS-Stimulated Inflammatory Responses via Inhibition of ERK/NF-κB Signaling Pathway and Anti-Atopic Dermatitis-like Effects in 2,4-Dinitrochlorobezene-Induced BALB/c Mice

So-Yeon Kim et al.

Summary: The study demonstrated that Mentha arvensis essential oil (MAEO) exerts anti-inflammatory effects in an atopic dermatitis (AD) model by inhibiting the ERK/NF-kappa B signaling pathway.

ANTIOXIDANTS (2021)

Article Immunology

Protectin D1 reduces imiquimod-induced psoriasiform skin inflammation

Kyung-Duck Park et al.

Summary: Specialized proresolving mediators are natural molecules derived from polyunsaturated fatty acids with potent anti-inflammatory properties. These mediators modulate cytokine expression and cell signaling pathways, demonstrating therapeutic potential in animal models of psoriasis.

INTERNATIONAL IMMUNOPHARMACOLOGY (2021)

Article Biochemistry & Molecular Biology

Ophiopogonin D ameliorates DNCB-induced atopic dermatitis-like lesions in BALB/c mice and TNF-α- inflamed HaCaT cell

Eun-Jin An et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

DHA and its derived lipid mediators MaR1, RvD1 and RvD2 block TNF-α inhibition of intestinal sugar and glutamine uptake in Caco-2 cells

Rosa Castilla-Madrigal et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2020)

Review Pharmacology & Pharmacy

New and Emerging Systemic Treatments for Atopic Dermatitis

Megan Newsom et al.

DRUGS (2020)

Review Dermatology

Atopic dermatitis: the skin barrier and beyond

T. Tsakok et al.

BRITISH JOURNAL OF DERMATOLOGY (2019)

Article Allergy

Pathophysiology of atopic dermatitis: Clinical implications

Jihyun Kim et al.

ALLERGY AND ASTHMA PROCEEDINGS (2019)

Review Pharmacology & Pharmacy

Therapeutic utility of glucocorticoids and antihistamines cotreatment. Rationale and perspectives

Carlos D. Zappia et al.

PHARMACOLOGY RESEARCH & PERSPECTIVES (2019)

Article Medicine, Research & Experimental

Anti-inflammatory effect of quercetin and galangin in LPS-stimulated RAW264.7 macrophages and DNCB-induced atopic dermatitis animal models

Hae Nim Le et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)

Review Allergy

Immunologic, microbial, and epithelial interactions in atopic dermatitis

Patrick M. Brunner et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2018)

Review Allergy

Significance of Skin Barrier Dysfunction in Atopic Dermatitis

Byung Eui Kim et al.

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH (2018)

Review Microbiology

The Gut Microbiome as a Major Regulator of the Gut-Skin Axis

Iman Salem et al.

FRONTIERS IN MICROBIOLOGY (2018)

Review Immunology

Microbiome and Allergic Diseases

Mariona Pascal et al.

FRONTIERS IN IMMUNOLOGY (2018)

Article Multidisciplinary Sciences

Resolvin E1 attenuates murine psoriatic dermatitis

Yu Sawada et al.

SCIENTIFIC REPORTS (2018)

Review Immunology

Maintenance of intestinal homeostasis by mucosal barriers

Ryu Okumura et al.

INFLAMMATION AND REGENERATION (2018)

Review Microbiology

A review of metabolic potential of human gut microbiome in human nutrition

Monika Yadav et al.

ARCHIVES OF MICROBIOLOGY (2018)

Article Dermatology

The Short-Chain Fatty Acid Sodium Butyrate Functions as a Regulator of the Skin Immune System

Agatha Schwarz et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2017)

Review Neurosciences

Interactions between the microbiota, immune and nervous systems in health and disease

Thomas C. Fung et al.

NATURE NEUROSCIENCE (2017)

Review Biology

The human microbiome in evolution

Emily R. Davenport et al.

BMC BIOLOGY (2017)

Article Medicine, General & Internal

Allergy associations with the adult fecal microbiota: Analysis of the American Gut Project

Xing Hua et al.

EBIOMEDICINE (2016)

Review Allergy

Role of omega-3 fatty acids and their metabolites in asthma and allergic diseases

Jun Miyata et al.

ALLERGOLOGY INTERNATIONAL (2015)

Review Allergy

Atopic dermatitis and the atopic march revisited

S. C. Dharmage et al.

ALLERGY (2014)

Article Biochemistry & Molecular Biology

Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes

Chisato Kusunoki et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Review Cell Biology

Role of Macrophages in the Pathogenesis of Atopic Dermatitis

Sadaf Kasraie et al.

MEDIATORS OF INFLAMMATION (2013)

Review Allergy

Epidermal Barrier in Atopic Dermatitis

Byung Eui Kim et al.

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH (2012)

Article Gastroenterology & Hepatology

Probiotics in Perspective

Fergus Shanahan

GASTROENTEROLOGY (2010)

Article Dermatology

Topical application with a new NF-κB inhibitor improves atopic dermatitis in NC/NgaTnd mice

Akane Tanaka et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)

Article Nutrition & Dietetics

Probiotic effects on inflammatory bowel disease

Barbara Sheil et al.

JOURNAL OF NUTRITION (2007)

Review Biochemistry & Molecular Biology

Inducible nitric oxide synthase and inflammatory diseases

R Zamora et al.

MOLECULAR MEDICINE (2000)