Journal
INTERNAL MEDICINE JOURNAL
Volume 53, Issue 7, Pages 1284-1287Publisher
WILEY
DOI: 10.1111/imj.16159
Keywords
repurposing; generic; medicine; off-label; off-patent
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With the rising costs of drug development, the reutilization of low-cost medicines for new indications is becoming increasingly important. However, there are various obstacles to repurposing, especially for off-patent medicines, and limited motivation for the pharmaceutical industry to sponsor registration and public subsidy listing. In this article, we examine these barriers and their implications, and present successful examples of repurposing strategies.
With the increasing costs of drug development, repurposing of low-cost medicines for new indications has never been more important. However, there are multiple barriers to repurposing, particularly for off-patent medicines, and limited incentives for the pharmaceutical industry to sponsor registration and public subsidy listing. Here, we explore these barriers and their consequences and provide examples of successful repurposing strategies.
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