Journal
CHEMICAL COMMUNICATIONS
Volume 51, Issue 83, Pages 15241-15244Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc05551b
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Funding
- National Nature Science Foundation of China [21102021, 81473082]
- Nature Science Foundation of Guangdong Province, China [S2011040004201]
- Science and Technology Program of Guangzhou [201508020016]
- Science and Technology Program of Guangdong Province [2012B020306007]
- Guangdong Province Higher Education Qianbaishi Engineering project
- Guangdong University of Technology Pei Ying Yu Cai Project
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A new RNA-selective fluorescent dye integrated with a thiazole orange and a p-(methylthio) styryl moiety shows better nucleolus RNA staining and imaging performance in live cells than the commercial stains. It also exhibits excellent photostability, cell tolerance, and counterstain compatibility with 4',6-diamidino-2-phenylindole for specific RNA-DNA colocalization in bioassays.
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