The new coumarin derivative cyclotetraphosphazene fluorometric chemosensor with reversible, high selective and sensitive for Fe3+ion detection

A new coumarin-based cyclotetraphosphazene molecule (OCCTP) that can show fluorescence and chemosensory properties has been designed and synthesized. For this purpose, the 7-hydroxy-3-(3,4,5-trimethoxyphenyl) coumarin (4) was synthesized.For the first time in this study, compound 4 which solid state structure and ge-ometry were determined by using crystal X-ray structural analysis were crystallized in the orthorhombic Fdd2 space group. The purified compounds were structurally characterized by elemental analysis, NMR (1H, 13C and 31P) and FT-IR spectroscopy, and mass analysis. Photophysical and chemosensory properties of OCCTP against a range of analytes (various metal ions) were investigated by UV-vis and Fluorescent Spectrophotometer. As a result of fluorimetric studies, OCCTP was found to be a Turn-Off fluorescent chemosensor against Fe3+ ions. The limit of detection (LOD) of OCCTP for Fe3+ was calculated as 1.87 mu M and its complex stoichiometry was determined as 1:2 (L/M) as a result of Job's plot. The reversibility study of the iron complex with EDTA showed that the free OCCTP chemosensor regenerated causing an increase in the fluorescence intensity of EDTA. The results showed that the newly synthesized coumarin-based cyclotetraphosphazene compound (OCCTP) can be used as a reversible, highly selective and sensitive fluorescent chemosensor (Turn-Off) which responds imme-diately against Fe3+ ions.

Automated summary

A new coumarin-based cyclotetraphosphazene molecule (OCCTP) has been designed and synthesized, which exhibits fluorescence and chemosensory properties. The solid state structure and geometry of compound 4 were determined using crystal X-ray structural analysis. The photophysical and chemosensory properties of OCCTP were investigated, and it was found to be a Turn-Off fluorescent chemosensor for Fe3+ ions. The newly synthesized OCCTP compound can serve as a reversible, highly selective, and sensitive fluorescent chemosensor for Fe3+ ions.