4.7 Article

A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 62, Pages 12490-12493

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc03807c

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Funding

  1. Singapore National Research Foundation Investigatorship [R279-000-444-281]
  2. Ministry of Defence [R229-000-340-232]
  3. Economic Development Board (Singapore-Peking-Oxford Research Enterprise) [COY-15-EWIRCFSA/N197-1]
  4. 973 project of MoST of China

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We report the design and synthesis of a red fluorescent AIE light-up probe for selective recognition, naked-eye detection, and image-guided photodynamic killing of Gram-positive bacteria, including vancomycin-resistant Enterococcus strains.

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