4.7 Article

(E)-Specific direct Julia-olefination of aryl alcohols without extra reducing agents promoted by bases

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 36, Pages 7729-7732

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc01965f

Keywords

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Funding

  1. National Natural Science Foundation of China [NSFC 21404096, U1463202]
  2. Fundamental Research Funds for the Central Universities of China [WK2060190022, WK2060190026]
  3. USTC

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An unprecedented base-promoted direct olefination of aryl alcohols with sulfones via a Julia-type reaction has been described. No extra reductants are needed for Julia reaction since alcohols work as double sources of aldehydes and the hydride. Generally high yields were given for both terminal and highly (E)-selective internal olefins.

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