4.7 Article

Iron-catalyzed asymmetric hydrosilylation of ketones

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 24, Pages 5073-5076

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc00612k

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Funding

  1. National Natural Science Foundation of China [21272255, 21422209, 21421091]

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A series of iron complexes of chiral iminopyridine-oxazoline (IPO) ligands have been synthesized. The most sterically hindered iron catalyst exhibits excellent activity (up to 99% yield) and high enantioselectivity (up to 93% ee) in asymmetric hydrosilylation of aryl ketones.

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