4.7 Article

pH-Responsive supramolecular vesicles assembled by water-soluble pillar[5]arene and a BODIPY photosensitizer for chemo-photodynamic dual therapy

Journal

CHEMICAL COMMUNICATIONS
Volume 51, Issue 76, Pages 14381-14384

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cc05785j

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Funding

  1. National Basic Research Program of China [2014CB846004, 2013CB922101]
  2. National Natural Science Foundation of China [21202083, 21472089]
  3. National Science Foundation of Jiangsu [BK20140595]

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Supramolecular vesicles which can successfully encapsulate DOX and exhibit rapid drug release in a low-pH environment are constructed based on the host-guest interaction of water-soluble pillar[5] arene and a BODIPY derivative. They show remarkable combination of chemo- and photodynamic activities, suggesting a promising drug nanocarrier.

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