4.5 Review

Arterial Hypertension-clinical trials update 2023

Journal

HYPERTENSION RESEARCH
Volume 46, Issue 9, Pages 2159-2167

Publisher

SPRINGERNATURE
DOI: 10.1038/s41440-023-01359-y

Keywords

Blood pressure; Hypertension management; Resistant hypertension; chronotherapy; Stroke; Device based therapies

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This summary reviews the most important clinical trials published in 2022 and early 2023. It discusses new pharmacological approaches to treat resistant hypertension and new knowledge about the optimal timing of antihypertensive medication intake. The article focuses on optimal blood pressure treatment targets and acknowledges the problem of treatment and guideline inertia. Information about pregnancy-related hypertension and blood pressure control following percutaneous thrombectomy after ischemic stroke is presented. Finally, novel clinical data on device-based approaches to treat hypertension are summarized.
Arterial hypertension is associated with increased morbidity and mortality and research in the field is highly dynamic. This summary reviews the most important clinical trials published in 2022 and early 2023. Findings on new pharmacological approaches to treat resistant hypertension are presented and new knowledge about the optimal timing of the antihypertensive medication intake is discussed. It is focused on optimal blood pressure treatment targets and the problem of treatment and guideline inertia is acknowledged. Information about pregnancy-related hypertension is presented and blood pressure control following percutaneous thrombectomy after ischemic stroke is discussed. Finally, novel clinical data on device-based approaches to treat hypertension are summarized.

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